A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
about
Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor systemNetrin (UNC-6) mediates dendritic self-avoidanceGenetic dissection of the function of hindbrain axonal commissuresN-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptorsDscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal AxonsCellular Strategies of Axonal PathfindingIn the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS.Drosophila neurexin IV interacts with Roundabout and is required for repulsive midline axon guidanceThe homeodomain transcription factor Hb9 controls axon guidance in Drosophila through the regulation of Robo receptors.Axon guidance at the midline: of mice and flies.Transcription factors and effectors that regulate neuronal morphology.An instruction language for self-construction in the context of neural networks.A genome-wide analysis reveals that the Drosophila transcription factor Lola promotes axon growth in part by suppressing expression of the actin nucleation factor Spire.Localized netrins act as positional cues to control layer-specific targeting of photoreceptor axons in Drosophila.Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowthEquivalent Activities of Repulsive Axon Guidance Receptors.Reassessing ecdysteroidogenic cells from the cell membrane receptors' perspective.The Intracellular Domain of the Frazzled/DCC Receptor Is a Transcription Factor Required for Commissural Axon Guidance.Distinct functional domains of the Abelson tyrosine kinase control axon guidance responses to Netrin and Slit to regulate the assembly of neural circuits.Src inhibits midline axon crossing independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) receptor tyrosine phosphorylation.Requirement for commissureless2 function during dipteran insect nerve cord development.Evolution of the functionally conserved DCC gene in birdsNavigating intermediate targets: the nervous system midline.Axonal commissures in the central nervous system: how to cross the midline?Transcriptional regulation of guidance at the midline and in motor circuits.Crossing the embryonic midline: molecular mechanisms regulating axon responsiveness at an intermediate target.Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptorRobo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons.Sema-1a Reverse Signaling Promotes Midline Crossing in Response to Secreted Semaphorins.14-3-3ε couples protein kinase A to semaphorin signaling and silences plexin RasGAP-mediated axonal repulsion.Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion.Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2.Neuroscience. Crossing the line.Axon guidance pathways and the control of gene expression.Brain Tumor promotes axon growth across the midline through interactions with the microtubule stabilizing protein Apc2.Building Spinal and Brain Commissures: Axon Guidance at the Midline
P2860
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P2860
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@ast
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@en
type
label
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@ast
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@en
prefLabel
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@ast
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@en
P2093
P2860
P356
P1433
P1476
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance
@en
P2093
David S Garbe
Greg J Bashaw
P2860
P304
P356
10.1126/SCIENCE.1171320
P407
P577
2009-03-26T00:00:00Z