A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein
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Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient miceSpecific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenaseIndirubin-3'-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migrationDisruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoproteinOxidized low-density lipoprotein contributes to atherogenesis via co-activation of macrophages and mast cellsCeruloplasmin enhances smooth muscle cell- and endothelial cell-mediated low density lipoprotein oxidation by a superoxide-dependent mechanism.The role of lipid peroxidation in arteriosclerosis.Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells.The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation.Why are low-density lipoproteins atherogenic?The role of oxidative stress in atherosclerosis: the hope and the hypeOxidized low density lipoprotein: atherogenic and proinflammatory characteristics during macrophage foam cell formation. An inhibitory role for nutritional antioxidants and serum paraoxonase.Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesionsGene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesionsCardiovascular disease and nutrient antioxidants: role of low-density lipoprotein oxidation.Opposite effects of methanandamide on lipopolysaccharide-induced prostaglandin E2 and F2α synthesis in uterine explants from pregnant mice.Oxidized LDL triggers pro-oncogenic signaling in human breast mammary epithelial cells partly via stimulation of MiR-21Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Absence of an effect of vitamin E on protein and lipid radical formation during lipoperoxidation of LDL by lipoxygenase.The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease.Role of monocytes in atherogenesis.Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein. Use of a new water-soluble probucol derivative.Immunomodulation and vaccination for atherosclerosis.In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals.Oxidized low-density lipoprotein.Eicosanoids and renal damage in cardiometabolic syndrome.Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis.Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells.Macrophages and oxidized low density lipoproteins in the pathogenesis of atherosclerosis.Cellular oxidative modification of low density lipoprotein does not require lipoxygenases.Cellular signaling and potential new treatment targets in diabetic retinopathy.Leukotriene signaling in atherosclerosis and ischemiaRole of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cellsWhy targeting HDL should work as a therapeutic tool, but has not.Biochemistry of the arterial wall in developing atherosclerosis.Do atherosclerosis and obesity-associated susceptibility to cancer share causative link to oxLDL and LOX-1?Mitochondria in vascular disease.Role of oxidized low density lipoprotein in atherogenesis.Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein.
P2860
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P2860
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
A role for endothelial cell li ...... ion of low density lipoprotein
@ast
A role for endothelial cell li ...... ion of low density lipoprotein
@en
type
label
A role for endothelial cell li ...... ion of low density lipoprotein
@ast
A role for endothelial cell li ...... ion of low density lipoprotein
@en
prefLabel
A role for endothelial cell li ...... ion of low density lipoprotein
@ast
A role for endothelial cell li ...... ion of low density lipoprotein
@en
P2093
P2860
P356
P1476
A role for endothelial cell li ...... ion of low density lipoprotein
@en
P2093
D Steinberg
S Parthasarathy
P2860
P304
P356
10.1073/PNAS.86.3.1046
P407
P577
1989-02-01T00:00:00Z