The two subunits of the human asialoglycoprotein receptor have different fates when expressed alone in fibroblasts.
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Basolateral sorting signals differ in their ability to redirect apical proteins to the basolateral cell surfaceIn vitro binding of the asialoglycoprotein receptor to the beta adaptin of plasma membrane coated vesiclesAsialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor.Endocytosis and recycling of subunit H1 of the asialoglycoprotein receptor is independent of oligomerization with H2.Assembly of a heterooligomeric asialoglycoprotein receptor complex during cell-free translation.Efficient gene transfer into human hepatocytes by baculovirus vectorsBiosynthetic transport of the asialoglycoprotein receptor H1 to the cell surface occurs via endosomes.The gamma and epsilon subunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors.Epitope structure of the carbohydrate recognition domain of asialoglycoprotein receptor to a monoclonal antibody revealed by high-resolution proteolytic excision mass spectrometry.The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acid alpha 2,6GalNAcNeisseria gonorrhoeae utilizes and enhances the biosynthesis of the asialoglycoprotein receptor expressed on the surface of the hepatic HepG2 cell line.Sendai virus efficiently infects cells via the asialoglycoprotein receptor and requires the presence of cleaved F0 precursor proteins for this alternative route of cell entry.Intracellular degradation of unassembled asialoglycoprotein receptor subunits: a pre-Golgi, nonlysosomal endoproteolytic cleavage.Polarized endocytosis by Madin-Darby canine kidney cells transfected with functional chicken liver glycoprotein receptor.Oligomeric structure of the human asialoglycoprotein receptor: nature and stoichiometry of mutual complexes containing H1 and H2 polypeptides assessed by fluorescence photobleaching recovery.GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestrationtrans-Golgi retention of a plasma membrane protein: mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit H1 result in trans-Golgi retention.Nonlysosomal, pre-Golgi degradation of unassembled asialoglycoprotein receptor subunits: a TLCK- and TPCK-sensitive cleavage within the ER.Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits.Endocytosis by the asialoglycoprotein receptor is independent of cytoplasmic serine residues.H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid.The minor subunit splice variants, H2b and H2c, of the human asialoglycoprotein receptor are present with the major subunit H1 in different hetero-oligomeric receptor complexes.Gonococcal lipooligosaccharide is a ligand for the asialoglycoprotein receptor on human sperm.Closely related mammals have distinct asialoglycoprotein receptor carbohydrate specificities.Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention.Degradation of T-cell receptor chains in the endoplasmic reticulum is inhibited by inhibitors of cysteine proteases.The transmembrane anchor of the T-cell antigen receptor beta chain contains a structural determinant of pre-Golgi proteolysis.Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex.Ligand-induced endocytosis of the asialoglycoprotein receptor: evidence for heterogeneity in subunit oligomerization.The endoplasmic reticulum degradation pathway for mutant secretory proteins alpha1-antitrypsin Z and S is distinct from that for an unassembled membrane protein.Signal peptidase can cleave inside a polytopic membrane protein.Determinants of oligomeric structure in the chicken liver glycoprotein receptor.Phorbol ester-induced redistribution of the ASGP receptor is independent of receptor phosphorylation.The human asialoglycoprotein receptor is a possible binding site for low-density lipoproteins and chylomicron remnants.Molecular cloning and expression of a new rat liver cell-CAM105 isoform. Differential phosphorylation of isoforms.Membrane-bound versus secreted forms of human asialoglycoprotein receptor subunits. Role of a juxtamembrane pentapeptide.Enhanced folding and processing of a disulfide mutant of the human asialoglycoprotein receptor H2b subunit.Characterization of the interaction of galactose-exposing particles with rat Kupffer cells.Early disulfide bond formation prevents heterotypic aggregation of membrane proteins in a cell-free translation system.Composition, antigenic properties and hepatocyte surface expression of the woodchuck asialoglycoprotein receptor.
P2860
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P2860
The two subunits of the human asialoglycoprotein receptor have different fates when expressed alone in fibroblasts.
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
The two subunits of the human ...... xpressed alone in fibroblasts.
@ast
The two subunits of the human ...... xpressed alone in fibroblasts.
@en
type
label
The two subunits of the human ...... xpressed alone in fibroblasts.
@ast
The two subunits of the human ...... xpressed alone in fibroblasts.
@en
prefLabel
The two subunits of the human ...... xpressed alone in fibroblasts.
@ast
The two subunits of the human ...... xpressed alone in fibroblasts.
@en
P2860
P356
P1476
The two subunits of the human ...... xpressed alone in fibroblasts.
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.4.1158
P407
P577
1989-02-01T00:00:00Z