5-Formylcytosine can be a stable DNA modification in mammals. - Wikidata - awgldk - TriplyDB

5-Formylcytosine can be a stable DNA modification in mammals.

5-Formylcytosine can be a stable DNA modification in mammals.

http://www.wikidata.org/entity/Q33840288

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DNA Methylation: Insights into Human Evolution Functions of TET Proteins in Hematopoietic Transformation Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications Role of TET enzymes in DNA methylation, development, and cancer Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3 Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification.High-throughput sequencing offers new insights into 5-hydroxymethylcytosine.Enrichment and fluorogenic labelling of 5-formyluracil in DNA Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships.Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis.Charting oxidized methylcytosines at base resolution.Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.DNA methylation and hydroxymethylation in hematologic differentiation and transformation.Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways.The role of active DNA demethylation and Tet enzyme function in memory formation and cocaine action.RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study.Quantification of Oxidized 5-Methylcytosine Bases and TET Enzyme Activity.In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine.Tet2 Catalyzes Stepwise 5-Methylcytosine Oxidation by an Iterative and de novo Mechanism.Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.5-Formylcytosine does not change the global structure of DNA.DNA modifications in models of alcohol use disorders.The expanding scope and impact of epigenetic cytosine modifications.Epigenetic mechanisms in neurogenesis.Are there specific readers of oxidized 5-methylcytosine bases?Dealing with an Unconventional Genetic Code in Mitochondria: The Biogenesis and Pathogenic Defects of the 5-Formylcytosine Modification in Mitochondrial tRNAMet.Epigenetic modification of nucleic acids: from basic studies to medical applications.The elusive role of 5'-hydroxymethylcytosine.2'-O-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA.Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells.In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?Fluorogenic labeling and single-base resolution analysis of 5-formylcytosine in DNA.The chemistries and consequences of DNA and RNA methylation and demethylation.

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5-Formylcytosine can be a stable DNA modification in mammals.

http://www.wikidata.org/entity/Q33840288

description

2015 nî lūn-bûn

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2015 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2015 թվականի հունիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

5-Formylcytosine can be a stable DNA modification in mammals.

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5-Formylcytosine can be a stable DNA modification in mammals.

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type

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5-Formylcytosine can be a stable DNA modification in mammals.

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5-Formylcytosine can be a stable DNA modification in mammals.

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prefLabel

5-Formylcytosine can be a stable DNA modification in mammals.

@ast

5-Formylcytosine can be a stable DNA modification in mammals.

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Nature Chemical Biology

P1476

5-Formylcytosine can be a stable DNA modification in mammals.

@en

P2093

Heather E Burgess

http://www.w3.org/2001/XMLSchema#string

Martin Bachman

http://www.w3.org/2001/XMLSchema#string

Santiago Uribe-Lewis

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Wolf Reik

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Xiaoping Yang

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P2860

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

The ground state of embryonic stem cell self-renewal

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555-557

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10.1038/NCHEMBIO.1848

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8

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11

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Shankar Balasubramanian

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2015-06-22T00:00:00Z

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1021651811

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26098680

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5486442

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