Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes. - Wikidata - awgldk - TriplyDB

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

http://www.wikidata.org/entity/Q33840423

about

Deletional tolerance mediated by extrathymic Aire-expressing cells Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression Genetics, pathogenesis and clinical interventions in type 1 diabetes Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells Autoimmune responses in T1DM: quantitative methods to understand onset, progression, and prevention of disease Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes Stem cell treatment for type 1 diabetes.Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage.Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit.Caspase-3 is involved in IFN-γ- and TNF-α-mediated MIN6 cells apoptosis via NF-κB/Bcl-2 pathway.High-throughput sequencing of islet-infiltrating memory CD4+ T cells reveals a similar pattern of TCR Vβ usage in prediabetic and diabetic NOD mice Induction of indoleamine 2, 3-dioxygenase in human dendritic cells by a cholera toxin B subunit-proinsulin vaccine.T cell-driven initiation and propagation of autoimmune diabetes Complete diabetes protection despite delayed thymic tolerance in NOD8.3 TCR transgenic mice due to antigen-induced extrathymic deletion of T cells.Mouse liver-specific CD8(+) T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes.Making the most of major histocompatibility complex molecule multimers: applications in type 1 diabetes.Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes.Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells Perceiving the avidity of T cell activation can be translated into peripheral T cell regulation.Immunotherapy for the prevention and treatment of type 1 diabetes.T-cell avidity and tuning: the flexible connection between tolerance and autoimmunity.Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signaling Characterization of Diabetogenic CD8+ T Cells: IMMUNE THERAPY WITH METABOLIC BLOCKADE.Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities.The specificity of T cell regulation that enables self-nonself discrimination in the periphery.Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes.Changes in autoreactive T cell avidity during type 1 diabetes development.Transgenically induced GAD tolerance curtails the development of early beta-cell autoreactivities but causes the subsequent development of supernormal autoreactivities to other beta-cell antigens.Viral triggers for autoimmunity: is the 'glass of molecular mimicry' half full or half empty?Immunological perspective of self versus tumor antigens: insights from the RIP-gp model.Bone marrow stem cell as a potential treatment for diabetes.Effector and regulatory T cell subsets in diabetes-associated inflammation. Is there a connection with ST2/IL-33 axis? Perspective.Therapeutic potential of umbilical cord blood cells for type 1 diabetes mellitus.Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation.C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?Role of TGF-β in Self-Peptide Regulation of Autoimmunity.Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.

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P2860

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

http://www.wikidata.org/entity/Q33840423

description

2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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type

label

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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prefLabel

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

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P1433

Journal of Clinical Investigation

P1476

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

@en

P2093

Abdelaziz Amrani

http://www.w3.org/2001/XMLSchema#string

Bingye Han

http://www.w3.org/2001/XMLSchema#string

John F Elliott

http://www.w3.org/2001/XMLSchema#string

Jun Yamanouchi

http://www.w3.org/2001/XMLSchema#string

Pau Serra

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Pere Santamaria

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Peter Dickie

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Teresa P Dilorenzo

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P2860

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

Antibody multispecificity mediated by conformational diversity

Structural insights into the evolution of an antibody combining site

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen

Control of MHC restriction by TCR Valpha CDR1 and CDR2

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.

RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes

Effector lymphocytes in autoimmunity.

The specificity of TCR/pMHC interaction.

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1879-1887

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10.1172/JCI24219

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7

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115

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15937548

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1142112

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