about
Total synthesis of glycosylated proteinsGlycosylation variants of a β-glucosidase secreted by a Taiwanese fungus, Chaetomella raphigera, exhibit variant-specific catalytic and biochemical propertiesDevelopment and application of serine/threonine ligation for synthetic protein chemistry.Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins.Specificity of O-glycosylation in enhancing the stability and cellulose binding affinity of Family 1 carbohydrate-binding modulesSynthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity.Chemical synthesis of syndecan-3 glycopeptides bearing two heparan sulfate glycan chains.Chemical synthesis of the β-subunit of human luteinizing (hLH) and chorionic gonadotropin (hCG) glycoprotein hormonesDirect arginine modification in native peptides and application to chemical probe development.Intramolecular N-glycan/polypeptide interactions observed at multiple N-glycan remodeling steps through [(13)C,(15)N]-N-acetylglucosamine labeling of immunoglobulin G1.Total synthesis of homogeneous variants of hirudin P6: a post-translationally modified anti-thrombotic leech-derived protein.N-terminal modification of proteins with o-aminophenols.Screening of a virtual mirror-image library of natural products.Fully Synthetic Granulocyte Colony-Stimulating Factor Enabled by Isonitrile-Mediated Coupling of Large, Side-Chain-Unprotected PeptidesProduction of homogeneous glycoprotein with multisite modifications by an engineered N-glycosyltransferase mutant.Chemical Methods for Encoding and Decoding of Posttranslational ModificationsHigh Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension.Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.Synthesis of granulocyte-macrophage colony-stimulating factor as homogeneous glycoforms and early comparisons with yeast cell-derived material.Resolving the α-glycosidic linkage of arginine-rhamnosylated translation elongation factor P triggers generation of the first ArgRha specific antibody.Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics.Using glyco-engineering to produce therapeutic proteins.Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.Chemical synthesis of erythropoietin glycoforms for insights into the relationship between glycosylation pattern and bioactivityStabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites.Site-selective protein-modification chemistry for basic biology and drug development.Erythropoietin and co.: intrinsic structure and functional disorder.Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology.Combination of Thiol-Additive-Free Native Chemical Ligation/Desulfurization and Intentional Replacement of Alanine with Cysteine.A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis.Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease.Synthesis of tumor necrosis factor α for use as a mirror-image phage display targetIron-Catalyzed Direct Diazidation for a Broad Range of Olefins.Molecular-scale features that govern the effects of O-glycosylation on a carbohydrate-binding module.Solid-phase supported design of carriers for therapeutic nucleic acid delivery.Sequential one-pot enzymatic synthesis of oligo-N-acetyllactosamine and its multi-sialylated extensions.Chemistry. Improving biologic drugs via total chemical synthesis.Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines.Targeting the N terminus for site-selective protein modification.Occurrence of free sialyl oligosaccharides related to N-glycans (sialyl free N-glycans) in animal sera.
P2860
Q28083496-574317DB-2A00-48FC-8755-768A8D1DC134Q28542700-76C81574-24C6-4D75-AD08-AEA89533388DQ30362103-2F3B64E5-50C2-4EA1-9417-B88222AEAA74Q30387202-75270D82-A73A-4509-AA57-D8D366355C01Q33694343-D79859B2-2A42-40BE-81BE-EB527C48B7AEQ34060919-25DD07C7-3750-4A2C-BB42-A3E6F6899671Q34069807-304C8ED7-6245-4C46-9233-F372A31123B0Q34489536-FDCA6F2F-10E1-4CE3-B28A-12641905D73CQ34699009-A5A00F3A-2CE8-4933-996A-BE735EEE47B2Q34999126-0B597969-07B6-4074-AC27-3355E5A4D53FQ35116875-72E1C2E9-7F44-4E57-9658-9834D2FB09C6Q35157563-921A3E4B-86A5-4E44-8CD1-EF967016D5C0Q36023171-8BB52969-B2D6-4A70-BE0F-878DC722025DQ36198586-5C5EC2FD-C920-466E-B42D-579AE60B909DQ36337312-0946BC1D-4C82-4F3F-BD4B-CBC1695EBEE8Q36654176-412B83D1-C266-471B-ACF7-86201E079A7AQ36659566-4FA72CE0-354E-4B85-A386-050D0C61A005Q37581781-009B401E-BA5D-41AC-8C9B-6A46D0A17268Q37612674-CF1605BE-4ACB-4FE5-B6B3-E735ACA36933Q37718581-B5A45B9F-BB23-4418-BFB3-3D2B4130AEBFQ38533442-0793A57C-55E6-423A-BD14-5B7ACFA7C235Q38547311-B3099462-ACCC-4909-B326-A1ED660423CCQ38705725-C92118D6-2CB2-4F0E-B9DA-A13DBAD60D0EQ38798391-23B0C0C9-EA35-4395-9547-8EA3F290F077Q38802664-21C696E9-173E-4023-9492-7586F9D12819Q38918179-A75B8304-4E55-45EA-8549-0A7193DD85B8Q39005050-1A40A9A6-46E8-4322-8AB3-FAA745500062Q39325962-5D3ED545-205E-4EC5-8545-15B498A25E6CQ39402878-65F9A6A6-8D65-402A-8255-1545B332E613Q40092320-209CF654-1ACC-4BEE-ABB9-AE4E259C98C0Q40626138-351AD6C9-73A8-4402-835A-B6143CA51B55Q41815869-86A2CD5C-D752-4E8B-9498-F817697DFCE1Q41855560-4F4721CF-BD6A-43A5-B1D5-245ADED8F7FFQ42120158-9FFDC3FF-4692-42BB-9A93-93CFBB15FB3FQ42921833-9A81E2F5-AF8B-499D-B40C-A30CD1345F58Q43021418-6BD1841A-F7AC-4246-B2F7-AD3D0D7A3171Q46078003-293CCB8B-B5E3-44DF-B299-EB4EC50B0F25Q46081185-E2D28EBC-E807-45B0-AA98-1E4860BF7F75Q46463952-FB28FABC-8699-46DC-BD2F-A1CEEE3D009CQ46560069-2BAE9F8B-4349-434D-BA54-942981AB1C77
P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Erythropoietin derived by chemical synthesis.
@ast
Erythropoietin derived by chemical synthesis.
@en
type
label
Erythropoietin derived by chemical synthesis.
@ast
Erythropoietin derived by chemical synthesis.
@en
prefLabel
Erythropoietin derived by chemical synthesis.
@ast
Erythropoietin derived by chemical synthesis.
@en
P2093
P2860
P356
P1433
P1476
Erythropoietin derived by chemical synthesis.
@en
P2093
Jae-Hung Shieh
Malcolm A S Moore
Ronald Hendrickson
Samuel J Danishefsky
Suwei Dong
P2860
P304
P356
10.1126/SCIENCE.1245095
P407
P577
2013-12-01T00:00:00Z