Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.

Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.

Item
http://www.wikidata.org/entity/Q33840785
Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels.Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain.Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacChimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivationDiscovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties.(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currentsSynthesis and Evaluation of Novel α-Aminoamides Containing an Indole Moiety for the Treatment of Neuropathic Pain.
P2860

Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.

Item
http://www.wikidata.org/entity/Q33840785
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Merging the structural motifs ...... ant anticonvulsant activities.
@ast
Merging the structural motifs ...... ant anticonvulsant activities.
@en
type
label
Merging the structural motifs ...... ant anticonvulsant activities.
@ast
Merging the structural motifs ...... ant anticonvulsant activities.
@en
prefLabel
Merging the structural motifs ...... ant anticonvulsant activities.
@ast
Merging the structural motifs ...... ant anticonvulsant activities.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Merging the structural motifs ...... ant anticonvulsant activities.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932