A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
about
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infectionDiametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunologyImmunology in wild nonmodel rodents: an ecological context for studies of health and diseaseThe impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in miceFcγ Receptors in Solid Organ TransplantationImmune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodesFcγRIIB and autoimmunity.Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patientsAssociation of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal StudiesInfection in systemic lupus erythematosus, similarities, and differences with lupus flare.Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease.Copy number, linkage disequilibrium and disease association in the FCGR locus.Defunctioning polymorphism in the immunoglobulin G inhibitory receptor (FcγRIIB-T/T232) does not impact on kidney transplant or recipient survival.Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice.FCGR2B and FCRLB gene polymorphisms associated with IgA nephropathy.FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesisFunctional Fcgamma receptor polymorphisms are associated with human allergy.High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.Characterization of the biological processes shaping the genetic structure of the Italian population.Evolutionary history of copy-number-variable locus for the low-affinity Fcγ receptor: mutation rate, autoimmune disease, and the legacy of helminth infection.Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.Possible influence of resistance to malaria in clinical presentation of rheumatoid arthritis: biological significance of natural selection.Distribution of FcγR gene polymorphisms among two sympatric populations in Mali: differing allele frequencies, associations with malariometric indices and implications for genetic susceptibility to malariaRegulation of allograft survival by inhibitory FcγRIIb signalingComprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-AnalysisToll-like receptor 7 mediates early innate immune responses to malaria.LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232.FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.FcγRIIB: a modulator of cell activation and humoral tolerance.Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases.B-cell regulation and its application to transplantation.Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus.Targeting B cells and autoantibodies in the therapy of autoimmune diseases.B-cell biomarkers in transplantation--from genes to therapy.Immunomodulation by IVIg and the Role of Fc-Gamma Receptors: Classic Mechanisms of Action after all?Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine.Regulatory B cells mediate tolerance to apoptotic self in health: implications for disease.
P2860
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P2860
A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@ast
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@en
type
label
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@ast
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@en
prefLabel
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@ast
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@en
P2093
P2860
P50
P356
P1476
A defunctioning polymorphism i ...... o systemic lupus erythematosus
@en
P2093
Heather A Niederer
J Anthony G Scott
Kenneth G C Smith
Lisa C Willcocks
Norbert Peshu
Paul A Lyons
Wanling Yang
Yu Lung Lau
P2860
P304
P356
10.1073/PNAS.0915133107
P407
P577
2010-04-12T00:00:00Z