Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. - Wikidata - awgldk - TriplyDB

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

http://www.wikidata.org/entity/Q33847391

about

Prospects for lentiviral vector mediated prostaglandin F synthase gene delivery in monkey eyes in vivo Corneal gene therapy: basic science and translational perspective Exciting directions in glaucoma Application of canaloplasty in glaucoma gene therapy: where are we?Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments.Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.Glaucoma: genes, phenotypes, and new directions for therapy.CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit Knockdown of NBCe1 in vivo compromises the corneal endothelial pump.Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain.Self-complementary adeno-associated viral vectors for gene therapy of hemophilia B: progress and challenges Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats Self-Complementary Adeno-Associated Virus Vectors Improve Transduction Efficiency of Corneal Endothelial Cells.Comparisons of actin filament disruptors and Rho kinase inhibitors as potential antiglaucoma medications Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork.Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy.Advances in glaucoma treatment and management: outflow drugs.A Potential Application of Canaloplasty in Glaucoma Gene Therapy Gene therapy strategies in glaucoma and application for steroid-induced hypertension Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2.Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia Outflow tract ablation using a conditionally cytotoxic feline immunodeficiency viral vector.Gene therapy for noninfectious uveitis.The cellular and molecular biology of the iris, an overlooked tissue: the iris and pseudoexfoliation glaucoma.Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy.The Pathway From Genes to Gene Therapy in Glaucoma: A Review of Possibilities for Using Genes as Glaucoma Drugs.Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis.Gene transfer to the outflow tract.Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye.Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors.Open-angle glaucoma: therapeutically targeting the extracellular matrix of the conventional outflow pathway.Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork.

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P2860

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

http://www.wikidata.org/entity/Q33847391

description

2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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Investigative Ophthalmology & Visual Science

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Self-complementary AAV virus ( ...... rk of living rats and monkeys.

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P2093

Carol A Rasmussen

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Eric C Porterfield

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LaKisha K Buie

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Paul L Kaufman

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Richard J Samulski

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Silva Markovic-Plese

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Teresa Borrás

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Vinod S Ramgolam

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Vivian W Choi

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P2860

Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

Gene expression in the trabecular meshwork and the influence of intraocular pressure.

Clinical protocol. An open-label, phase I, single administration, dose-escalation study of ADGVPEDF.11D (ADPEDF) in neovascular age-related macular degeneration (AMD).

Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta.

Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors

Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates.

P304

236-248

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10.1167/IOVS.09-3847

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1

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51

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Silva Markovic-Plese

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26745194

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19684004

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2869048

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