Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture
about
CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genomeThe interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathwaysRegulatory RNAs discovered in unexpected placesBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisA comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivationThe molecular basis of herpes simplex virus latencyAnti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcriptHerpes simplex virus type 1 (HSV-1)-induced apoptosis in human dendritic cells as a result of downregulation of cellular FLICE-inhibitory protein and reduced expression of HSV-1 antiapoptotic latency-associated transcript sequences.Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycleThe locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice.Small non-coding RNAs encoded within the herpes simplex virus type 1 latency associated transcript (LAT) cooperate with the retinoic acid inducible gene I (RIG-I) to induce beta-interferon promoter activity and promote cell survival.Three herpes simplex virus type 1 latency-associated transcript mutants with distinct and asymmetric effects on virulence in mice compared with rabbits.The 2.2-kilobase latency-associated transcript of herpes simplex virus type 2 does not modulate viral replication, reactivation, or establishment of latency in transgenic miceHerpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis.Identification of a novel herpes simplex virus type 1 transcript and protein (AL3) expressed during latency.A herpes simplex virus type 1 mutant expressing a baculovirus inhibitor of apoptosis gene in place of latency-associated transcript has a wild-type reactivation phenotype in the mouse.The herpes simplex virus type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c miceCellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice.A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levelsA mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo.Human herpesvirus latency.Virus and cell RNAs expressed during Epstein-Barr virus replicationStable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosisThe stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cellsInfection of cattle with a bovine herpesvirus 1 strain that contains a mutation in the latency-related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency.A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.Herpes simplex virus type 1 latently infected neurons differentially express latency-associated and ICP0 transcripts.Herpes simplex virus type 1 and bovine herpesvirus 1 latency.The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanismA herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation.Viral noncoding RNAs: more surprises.Localization of sequences in a protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 that inhibits apoptosis and interferes with Notch1-mediated trans-activation of the bICP0 promoter.Herpes simplex virus infection and apoptosis.HSV LAT and neuronal survival.Two microRNAs encoded within the bovine herpesvirus 1 latency-related gene promote cell survival by interacting with RIG-I and stimulating NF-κB-dependent transcription and beta interferon signaling pathways.Apoptosis and antigen receptor function in T and B cells following exposure to herpes simplex virusHSV trafficking and development of gene therapy vectors with applications in the nervous system.Influence of herpes simplex virus 1 latency-associated transcripts on the establishment and maintenance of latency in the ROSA26R reporter mouse modelDecreased reactivation of a herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation.
P2860
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P2860
Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Region of herpes simplex virus ...... ell survival in tissue culture
@ast
Region of herpes simplex virus ...... ell survival in tissue culture
@en
type
label
Region of herpes simplex virus ...... ell survival in tissue culture
@ast
Region of herpes simplex virus ...... ell survival in tissue culture
@en
prefLabel
Region of herpes simplex virus ...... ell survival in tissue culture
@ast
Region of herpes simplex virus ...... ell survival in tissue culture
@en
P2093
P2860
P1433
P1476
Region of herpes simplex virus ...... ell survival in tissue culture
@en
P2093
P2860
P304
P356
10.1128/JVI.75.8.3636-3646.2001
P50
P577
2001-04-01T00:00:00Z