Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.

Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.

Item
http://www.wikidata.org/entity/Q33853600
Contemporary murine models in preclinical astrocytoma drug developmentA kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastomaAn off-target nucleostemin RNAi inhibits growth in human glioblastoma-derived cancer stem cellsEvolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.Signal transduction molecule patterns indicating potential glioblastoma therapy approaches.Glioma: experimental models and reality.Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells.Current and future directions for Phase II trials in high-grade glioma.Circulating biomarker panels for targeted therapy in brain tumors.MicroRNA-26a promotes tumor growth and angiogenesis in glioma by directly targeting prohibitin.MicroRNA-625 inhibits the proliferation and increases the chemosensitivity of glioma by directly targeting AKT2.Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens.Shifting the balance of mitochondrial apoptosis: therapeutic perspectives.Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma.The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis.Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma.Current Challenges and Opportunities in Treating Glioblastoma.
P2860

Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.

Item
http://www.wikidata.org/entity/Q33853600
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Identification of novel synerg ...... thality screening against GBM.
@ast
Identification of novel synerg ...... thality screening against GBM.
@en
type
label
Identification of novel synerg ...... thality screening against GBM.
@ast
Identification of novel synerg ...... thality screening against GBM.
@en
prefLabel
Identification of novel synerg ...... thality screening against GBM.
@ast
Identification of novel synerg ...... thality screening against GBM.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Identification of novel synerg ...... thality screening against GBM.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932