Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes - Wikidata - awgldk - TriplyDB

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

http://www.wikidata.org/entity/Q33853935

about

Telomeric expression sites are highly conserved in Trypanosoma brucei Assembling the components of the quorum sensing pathway in African trypanosomes Microbial antigenic variation mediated by homologous DNA recombination NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions Unfolded Protein Response Pathways in Bloodstream-Form Trypanosoma brucei?Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies The RACK1 homologue from Trypanosoma brucei is required for the onset and progression of cytokinesis.The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages.Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum.Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.Chaperone requirements for biosynthesis of the trypanosome variant surface glycoprotein A quorum sensing-independent path to stumpy development in Trypanosoma brucei Lineage-specific proteins essential for endocytosis in trypanosomes.Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: making it and taking it.Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.Antigenic variation in African trypanosomes.Surface proteins, ERAD and antigenic variation in Trypanosoma brucei.DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes.Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity.Trypanosoma brucei ARF1 plays a central role in endocytosis and golgi-lysosome trafficking.The trypanosomatid-specific N terminus of RPA2 is required for RNA polymerase I assembly, localization, and function.RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection.Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex A MORN Repeat Protein Facilitates Protein Entry into the Flagellar Pocket of Trypanosoma brucei.FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei.Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.Dynein Light Chain LC8 Is Required for RNA Polymerase I-Mediated Transcription in Trypanosoma brucei, Facilitating Assembly and Promoter Binding of Class I Transcription Factor A Characterization of a novel class I transcription factor A (CITFA) subunit that is indispensable for transcription by the multifunctional RNA polymerase I of Trypanosoma brucei.A new approach to chemotherapy: drug-induced differentiation kills African trypanosomes.Cell cycle regulation in Trypanosoma brucei.Leishmania adaptor protein-1 subunits are required for normal lysosome traffic, flagellum biogenesis, lipid homeostasis, and adaptation to temperatures encountered in the mammalian host.VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes.Transgenic Leishmania and the immune response to infection RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei.Life and times: synthesis, trafficking, and evolution of VSG.cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target.VSG switching in Trypanosoma brucei: antigenic variation analysed using RNAi in the absence of immune selection.Let's get fISSical: fast in silico synchronization as a new tool for cell division cycle analysis.

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P2860

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

http://www.wikidata.org/entity/Q33853935

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2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Proceedings of the National Academy of Sciences of the United States of America

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Variant surface glycoprotein R ...... arrest in African trypanosomes

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Gloria Rudenko

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James Minchin

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Karen Sheader

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Katie Hughes

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Keith Gull

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Sue Vaughan

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P2860

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei.

Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite.

Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei.

The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations.

Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8

Procyclin null mutants of Trypanosoma brucei express free glycosylphosphatidylinositols on their surface

Endocytosis, membrane recycling and sorting of GPI-anchored proteins: Trypanosoma brucei as a model system.

Antigenic variation in Trypanosoma brucei: facts, challenges and mysteries.

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