Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
about
Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processesPhosphoinositides: tiny lipids with giant impact on cell regulationInositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognitionConformational Changes in Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase upon Substrate Binding: ROLE OF N-TERMINAL LOBE AND ENANTIOMERIC SUBSTRATE PREFERENCEInositol phosphate-induced stabilization of inositol 1,3,4,5,6-pentakisphosphate 2-kinase and its role in substrate specificityExpression, purification, crystallization and preliminary X-ray diffraction analysis of the apo form of InsP52-K fromArabidopsis thalianaThe regulation and function of inositol 1,4,5-trisphosphate 3-kinasesAn essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger productionNeural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinaseDisruption of inositol biosynthesis through targeted mutagenesis in Dictyostelium discoideum: generation and characterization of inositol-auxotrophic mutantsLarge-scale mRNA sequencing determines global regulation of RNA editing during brain development.Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.Wandering through the laboratory.Phosphoinositide signaling: new tools and insights.Roles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biologyA zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization.Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinasesHigh-Throughput Cloning of Temperature-Sensitive Caenorhabditis elegans Mutants with Adult Syncytial Germline Membrane Architecture Defects.Nuclear inositide signalling -- expansion, structures and clarification.The nucleolus exhibits an osmotically regulated gatekeeping activity that controls the spatial dynamics and functions of nucleolinA non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA.Do mammals make all their own inositol hexakisphosphate?Dual functions for the Schizosaccharomyces pombe inositol kinase Ipk1 in nuclear mRNA export and polarized cell growth.Zebrafish inositol polyphosphate kinases: new effectors of cilia and developmental signaling.Modulation of inositol polyphosphate levels regulates neuronal differentiationDefining signal transduction by inositol phosphates.Extracellular Mipp1 Activity Confers Migratory Advantage to Epithelial Cells during Collective Migration.Crystallization and Preliminary X-Ray Diffraction Analysis of a Mammal Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase.Chemical tools for interrogating inositol pyrophosphate structure and function.The role of inositol signaling in the control of apoptosisInositol pentakisphosphate mediates Wnt/beta-catenin signaling.The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function.mRNA nuclear export and human diseaseCrystallization and preliminary X-ray diffraction analysis of inositol 1,3,4,5,6-pentakisphosphate kinase from Arabidopsis thaliana.Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding.IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids.Arabidopsis inositol pentakisphosphate 2-kinase, AtIPK1, is required for growth and modulates phosphate homeostasis at the transcriptional level.InsP6-sensitive variants of the Gle1 mRNA export factor rescue growth and fertility defects of the ipk1 low-phytic-acid mutation in Arabidopsis.
P2860
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P2860
Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@ast
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@en
type
label
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@ast
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@en
prefLabel
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@ast
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@en
P2093
P2860
P356
P1476
Disruption of the mouse inosit ...... ibution of 2-kinase expression
@en
P2093
John Verbsky
Kory Lavine
Philip W Majerus
P2860
P304
P356
10.1073/PNAS.0503656102
P407
P577
2005-06-06T00:00:00Z