Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains. - Wikidata - awgldk - TriplyDB

Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains.

Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains.

http://www.wikidata.org/entity/Q33854277

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Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin.Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels.The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats Can BACE1 inhibition mitigate early axonal pathology in neurological diseases?Localization and regional distribution of p23/TMP21 in the brain.Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann-Pick type C disease pathogenesis.

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P2860

Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains.

http://www.wikidata.org/entity/Q33854277

description

2007 nî lūn-bûn

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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հունվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

Cellular distribution of gamma ...... veloping and adult rat brains.

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Cellular distribution of gamma ...... veloping and adult rat brains.

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type

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Cellular distribution of gamma ...... veloping and adult rat brains.

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Cellular distribution of gamma ...... veloping and adult rat brains.

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Cellular distribution of gamma ...... veloping and adult rat brains.

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Cellular distribution of gamma ...... veloping and adult rat brains.

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J.NEUROBIOLAGING.2006.12.005

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Neurobiology of Aging

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Cellular distribution of gamma ...... veloping and adult rat brains.

@en

P2093

A Kodam

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G Thinakaran

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K S Vetrivel

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S Kar

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P2860

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates

Presenilin 1 is required for maturation and cell surface accumulation of nicastrin

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10.1016/J.NEUROBIOLAGING.2006.12.005

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