Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors. - Wikidata - awgldk - TriplyDB

Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.

Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.

http://www.wikidata.org/entity/Q33854787

about

Honokiol: a novel natural agent for cancer prevention and therapy Emerging Phytochemicals for the Prevention and Treatment of Head and Neck Cancer Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis Inhibition of STAT3 by niclosamide synergizes with erlotinib against head and neck cancer.Therapeutic modulators of STAT signalling for human diseases Grape seed proanthocyanidins inhibit the invasive potential of head and neck cutaneous squamous cell carcinoma cells by targeting EGFR expression and epithelial-to-mesenchymal transition.Honokiol activates reactive oxygen species-mediated cytoprotective autophagy in human prostate cancer cells.Bioactive phytochemical proanthocyanidins inhibit growth of head and neck squamous cell carcinoma cells by targeting multiple signaling molecules.STAT3 signaling: anticancer strategies and challenges.Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner.Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.Inhibition of class I histone deacetylases in non-small cell lung cancer by honokiol leads to suppression of cancer cell growth and induction of cell death in vitro and in vivo.Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.Honokiol Eliminates Human Oral Cancer Stem-Like Cells Accompanied with Suppression of Wnt/ β -Catenin Signaling and Apoptosis Induction.Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.Regulation of Mucin 1 and multidrug resistance protein 1 by honokiol enhances the efficacy of doxorubicin-mediated growth suppression in mammary carcinoma cells.Honokiol sensitizes breast cancer cells to TNF-α induction of apoptosis by inhibiting Nur77 expression.Antineoplastic Effects of Honokiol on Melanoma.Honokiol inhibits androgen receptor activity in prostate cancer cells Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors.Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer Honokiol analogs: a novel class of anticancer agents targeting cell signaling pathways and other bioactivities.Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals.Honokiol targets mitochondria to halt cancer progression and metastasis.Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells.Honokiol inhibits bladder cancer cell invasion through repressing SRC-3 expression and epithelial-mesenchymal transition.Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells.Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα.Honokiol inhibits hypoxia-inducible factor-1 pathway.Overcoming resistance to cetuximab with honokiol, a small-molecule polyphenol.Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin.Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.Synergistic effect of honokiol and 5-fluorouracil on apoptosis of oral squamous cell carcinoma cells.Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells.Natural Antioxidants: Multiple Mechanisms to Protect Skin From Solar Radiation.

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Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.

http://www.wikidata.org/entity/Q33854787

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@ast

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@en

type

label

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@ast

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@en

prefLabel

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@ast

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@en

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1078-0432.CCR-10-0333

P1433

Clinical Cancer Research

P1476

Honokiol inhibits epidermal gr ...... th factor receptor inhibitors.

@en

P2093

Daniel B Neill

http://www.w3.org/2001/XMLSchema#string

Jack L Arbiser

http://www.w3.org/2001/XMLSchema#string

Neil E Bhola

http://www.w3.org/2001/XMLSchema#string

Quan Cai

http://www.w3.org/2001/XMLSchema#string

Rebecca J Leeman-Neill

http://www.w3.org/2001/XMLSchema#string

Sonali C Joyce

http://www.w3.org/2001/XMLSchema#string

Sufi M Thomas

http://www.w3.org/2001/XMLSchema#string

P2860

Honokiol, a multifunctional antiangiogenic and antitumor agent

Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival.

Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo

The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells

Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells

STAT3 as a therapeutic target in head and neck cancer

Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth

Nuclear factor-kappaB in cancer development and progression

Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis.

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2571-2579

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scholarly article

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10.1158/1078-0432.CCR-10-0333

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9

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16

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Jennifer Grandis

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2010-04-13T00:00:00Z

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20388852

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2871379

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