A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells.
about
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cellsB-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsCbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.Identifying mutation specific cancer pathways using a structurally resolved protein interaction network.Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Cbl: many adaptations to regulate protein tyrosine kinases.Beyond the RING: CBL proteins as multivalent adapters.Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversionCbl-3-deficient mice exhibit normal epithelial developmentT cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia.E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunity
P2860
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P2860
A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A direct interaction between t ...... a positive signal in T cells.
@ast
A direct interaction between t ...... a positive signal in T cells.
@en
type
label
A direct interaction between t ...... a positive signal in T cells.
@ast
A direct interaction between t ...... a positive signal in T cells.
@en
prefLabel
A direct interaction between t ...... a positive signal in T cells.
@ast
A direct interaction between t ...... a positive signal in T cells.
@en
P2093
P1433
P1476
A direct interaction between t ...... a positive signal in T cells.
@en
P2093
P304
P356
10.1016/S0960-9822(99)80090-6
P407
P577
1999-02-01T00:00:00Z