Cytochrome P450 substrate specificities, substrate structural templates and enzyme active site geometries.
about
Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6Quantitative structure-activity relationships (QSARs) within substrates of human cytochromes P450 involved in drug metabolism.Molecular modeling of human cytochrome P450-substrate interactions.Structure-activity relationship for human cytochrome P450 substrates and inhibitors.Roles of phenylalanine at position 120 and glutamic acid at position 222 in the oxidation of chiral substrates by cytochrome P450 2D6.Cunninghamella as a microbiological model for metabolism of histamine H(3) receptor antagonist 1-[3-(4-tert-butylphenoxy)propyl]piperidine.Reverse conservation analysis reveals the specificity determining residues of cytochrome P450 family 2 (CYP 2).Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.Change in enantioselectivity in bufuralol 1''-hydroxylation by the substitution of phenylalanine-120 by alanine in cytochrome P450 2D6.The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes.
P2860
Q28361814-DE963E14-721B-4134-B585-62ED6CCEC82BQ34494804-B9C377A2-FE08-494D-89BD-83C5D7AF42ACQ34627912-B59E0BE4-213A-4ACE-835B-EA382A8B3354Q34627917-D134F699-8B22-4825-A59D-A3388A8D5623Q36376115-3E73EC6C-1B26-4EBD-8CBB-4F1CCE64383EQ41471743-13377F2E-DC45-43CE-9CDF-3851B13A11D2Q42188010-8FCB86D0-4852-4AC0-A7C4-C792A6414E70Q42600668-A9E5DE09-E66F-4FC0-B273-7055CE275A55Q45139158-592448D2-6C69-4407-AE05-49B9A73E747DQ46208435-EDB8B507-C8F2-4CEC-A23D-717C0172B230
P2860
Cytochrome P450 substrate specificities, substrate structural templates and enzyme active site geometries.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@ast
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@en
type
label
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@ast
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@en
prefLabel
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@ast
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@en
P2093
P2860
P356
P1476
Cytochrome P450 substrate spec ...... enzyme active site geometries.
@en
P2093
Eddershaw PJ
Goldfarb PS
P2860
P356
10.1515/DMDI.1999.15.1.1
P577
1999-01-01T00:00:00Z