von Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets.
about
The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domainMolecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequencesMultiple substitutions in the von Willebrand factor gene that mimic the pseudogene sequence.O-linked carbohydrate of recombinant von Willebrand factor influences ristocetin-induced binding to platelet glycoprotein 1b.Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to plateletsPlatelet adhesion to extracellular matrices of cultured cells.Effects of different amino-acid substitutions in the leucine 694-proline 708 segment of recombinant von Willebrand factor.Angiodysplasia in von Willebrand Disease: Understanding the Clinical and Basic Science.Unique expression of von Willebrand factor by type IIA von Willebrand's disease endothelial cells.Guidelines for the diagnosis and management of von Willebrand disease in Italy.Type I von Willebrand disease, subtype 'platelet low': decreased platelet adhesion can be explained by low synthesis of von Willebrand factor in endothelial cells.Diagnosis and management of von Willebrand disease.
P2860
Q28776603-7D5D902C-5BE0-4A5D-84AE-B89ED297F4BBQ28776606-7A462E20-80F3-49E5-8872-45F0D8214FD3Q35100545-9A5349E2-9D46-4D54-8E84-88A614FF4A04Q35612966-A630F717-4164-4CAE-906A-76D16B6B7E0BQ36925330-E05ADD6F-2A39-4C29-BC47-7FD318C33D6BQ37711745-0785F22D-1A9E-49D0-8C26-CD2886CB172AQ38288495-A4B06F07-FA8A-4250-8BB1-C6943433EA9EQ39286115-BBB0D722-E124-4815-934C-26A03C8F1CADQ41616327-5C2DC79F-CC81-464A-AD8B-09D23EBDEAF7Q44117199-DD763CE4-2D37-4389-A6AB-7FF31E1ABD14Q45874714-BA0EED64-4759-4A7C-9B34-C050E5CB2C31Q45884955-48DCFCDC-4CC3-4BE2-BDAF-22ABD26BDBD6
P2860
von Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets.
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
von Willebrand factor synthesi ...... reased affinity for platelets.
@ast
von Willebrand factor synthesi ...... reased affinity for platelets.
@en
type
label
von Willebrand factor synthesi ...... reased affinity for platelets.
@ast
von Willebrand factor synthesi ...... reased affinity for platelets.
@en
prefLabel
von Willebrand factor synthesi ...... reased affinity for platelets.
@ast
von Willebrand factor synthesi ...... reased affinity for platelets.
@en
P2093
P2860
P356
P1476
von Willebrand factor synthesi ...... reased affinity for platelets.
@en
P2093
Federici AB
Mannucci PM
d'Alessio P
de Boer HC
de Groot PG
P2860
P304
P356
10.1073/PNAS.86.10.3793
P407
P577
1989-05-01T00:00:00Z