Proteasome inhibitors: a novel class of potent and effective antitumor agents.
about
Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomibClioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisonsWhy bortezomib cannot go with 'green'?Multiple myelomaSelective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitroLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisNew molecularly targeted therapies for lung cancerTherapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancerThe role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancerReduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cellsInvestigations of methylmercury-induced alterations in neurogenesisThe proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapyA Screen of FDA-Approved Drugs for Inhibitors of Zika Virus InfectionThrombotic microangiopathy associated with proteasome inhibitorsModulatory effects of bortezomib on host immune cell functionsAdvances in the understanding of mechanisms and therapeutic use of bortezomibNeuroendocrine differentiation and the ubiquitin-proteasome system in cancer: Partners or enemies?New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG)Boron chemicals in diagnosis and therapeuticsCharacterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunitComplementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341Systematic approaches to identify E3 ligase substratesMantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agentsTrial Watch: Proteasomal inhibitors for anticancer therapyMuscle cachexia: current concepts of intracellular mechanisms and molecular regulationProteasome function is required for platelet productionPSMB7 is associated with anthracycline resistance and is a prognostic biomarker in breast cancerThe ubiquitin-proteasome pathway and proteasome inhibitorsNovel CD20 monoclonal antibodies for lymphoma therapyActivation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cellsIdentification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombeBortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouseFrom bench to bedside: lessons learned in translating preclinical studies in cancer drug developmentVariation in drug sensitivity of malignant mesothelioma cell lines with substantial effects of selenite and bortezomib, highlights need for individualized therapyTargeting neuroblastoma stem cells with retinoic acid and proteasome inhibitorBortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myelomaProfound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodes
P2860
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P2860
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@ast
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@en
type
label
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@ast
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@en
prefLabel
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@ast
Proteasome inhibitors: a novel class of potent and effective antitumor agents.
@en
P2093
P1433
P1476
Proteasome inhibitors: a novel class of potent and effective antitumor agents
@en
P2093
D D Lazarus
E A Sausville
P J Elliott
V J Palombella
P304
P407
P577
1999-06-01T00:00:00Z