The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines.
about
Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organismsInteraction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cellsTACC1-chTOG-Aurora A protein complex in breast cancerCarcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulatorsThe centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosisAZU-1: a candidate breast tumor suppressor and biomarker for tumor progressionD-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryoCep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.The TACC domain identifies a family of centrosomal proteins that can interact with microtubulesRHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stabilityAberrations of TACC1 and TACC3 are associated with ovarian cancerCytoplasmic polyadenylation in mammalian oocyte maturationMAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationPredictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized MedicineTransforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatusA classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3TACC3 expression and localization in the murine egg and ovaryTransforming fusions of FGFR and TACC genes in human glioblastoma.FGFR1 and WT1 are markers of human prostate cancer progression.The transforming acidic coiled coil (TACC1) protein modulates the transcriptional activity of the nuclear receptors TR and RAR.Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness.TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancerThe Xenopus TACC homologue, maskin, functions in mitotic spindle assemblyCharacterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells.Inferring causal genomic alterations in breast cancer using gene expression data.Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus.Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeatsThe Fibroblast Growth Factor signaling pathwayThe transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.Isotype class switching and the pathogenesis of multiple myeloma.Centrosomal TACCtics.TACC3 is essential for EGF-mediated EMT in cervical cancerImpact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer.The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancerHigh expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis.FGFR3-TACC3: A novel gene fusion in cervical cancer.Transforming acidic coiled-coil 3 and Aurora-A interact in human thyrocytes and their expression is deregulated in thyroid cancer tissues.Structural and regulatory roles of nonmotor spindle proteins
P2860
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P2860
The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The third member of the transf ...... in various cancer cell lines.
@ast
The third member of the transf ...... in various cancer cell lines.
@en
type
label
The third member of the transf ...... in various cancer cell lines.
@ast
The third member of the transf ...... in various cancer cell lines.
@en
prefLabel
The third member of the transf ...... in various cancer cell lines.
@ast
The third member of the transf ...... in various cancer cell lines.
@en
P2093
P356
P1433
P1476
The third member of the transf ...... in various cancer cell lines.
@en
P2093
P304
P356
10.1006/GENO.1999.5829
P577
1999-06-01T00:00:00Z