Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity.
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The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob miceLysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice.Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass.Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis.Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasisAnthocyanin inhibits high glucose-induced hepatic mtGPAT1 activation and prevents fatty acid synthesis through PKCζ.Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingHigh-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet.Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob MiceMice deficient in glycerol-3-phosphate acyltransferase-1 have a reduced susceptibility to liver cancerOrigins of metabolic complications in obesity: adipose tissue and free fatty acid trafficking.Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidationSterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.Dissociating fatty liver and diabetesClinically Relevant Mechanisms of Lipid Synthesis, Transport, and Storage.How lipid droplets "TAG" along: Glycerolipid synthetic enzymes and lipid storage.Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F₂ male offspring via the F₁ male offspring.Late-onset increases in oxidative stress and other tumorigenic activities and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic.Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats.Update on glycerol-3-phosphate acyltransferases: the roles in the development of insulin resistance.Targeting Hepatic Glycerolipid Synthesis and Turnover to Treat Fatty Liver Disease
P2860
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P2860
Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@ast
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@en
type
label
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@ast
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@en
prefLabel
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@ast
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@en
P2093
P2860
P356
P1433
P1476
Glycerol-3-phosphate acyltrans ...... insulin resistance or obesity.
@en
P2093
Angela A Wendel
Gary W Cline
Rosalind A Coleman
P2860
P304
P356
10.2337/DB09-1380
P407
P577
2010-03-03T00:00:00Z