Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

Item
http://www.wikidata.org/entity/Q33869850
2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials.Distinct effects of anti-tumor necrosis factor combined therapy on TH1/TH2 balance in rheumatoid arthritis patientsTwo inhibitors of DNA-synthesis lead to inhibition of cytokine production via a different mechanism.Revisiting the immunomodulators tacrolimus, methotrexate, and mycophenolate mofetil: their mechanisms of action and role in the treatment of IBD.Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro.Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line.Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses.The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species.LD-aminopterin in the canine homologue of human atopic dermatitis: a randomized, controlled trial reveals dosing factors affecting optimal therapy.Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition.Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy.High-grade mature B-cell lymphoma with Burkitt-like morphology: results of a clinicopathological study of 72 Japanese patients.Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Anti-proliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP.Correlation of genetic polymorphisms with clinical outcomes in pemetrexed-treated advanced lung adenocarcinoma patients.
P2860

Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

Item
http://www.wikidata.org/entity/Q33869850
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@ast
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@en
type
label
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@ast
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@en
prefLabel
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@ast
Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
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P1476
P2093
P2860
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Methotrexate inhibits the firs ...... icacy in rheumatoid arthritis?
@en
P2093
P2860
P304
P31
P356
P407
P478
P50
P577
P5875
P698
P932