Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10
about
Biology of adeno-associated viral vectors in the central nervous systemAdeno Associated Viral Vector Delivered RNAi for Gene Therapy of SOD1 Amyotrophic Lateral SclerosisState-of-the-art human gene therapy: part I. Gene delivery technologiesPerinatal systemic gene delivery using adeno-associated viral vectorsAdeno-associated virus-mediated microRNA delivery and therapeuticsFighting against kidney diseases with small interfering RNA: opportunities and challengesSystemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan.Exosome-associated AAV vector as a robust and convenient neuroscience toolE Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV EvolutionStructure of neurotropic adeno-associated virus AAVrh.8.Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease.Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates.Gene therapy for the nervous system: challenges and new strategies.Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho(-/-) mouseMaking the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades.Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene TherapyA brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases.AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats.Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway.A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1.A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord.AAV-mediated gene delivery in a feline model of Sandhoff disease corrects lysosomal storage in the central nervous system.Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.Long-term Improvements in Lifespan and Pathology in CNS and PNS After BMT Plus One Intravenous Injection of AAVrh10-GALC in Twitcher MiceWidespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector.rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.Gene Therapy for the Treatment of Neurological Disorders: Metabolic Disorders.Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplantGlymphatic fluid transport controls paravascular clearance of AAV vectors from the brainSurvival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B.Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery.Thinking small: towards microRNA-based therapeutics for anxiety disorders.
P2860
Q21129328-97811C70-A34B-4DFA-B12D-78D09282B40EQ26741129-5C61F2C3-0916-4AA0-A1A1-D791FD99BD9BQ26825575-1F284F38-D84B-4678-A405-38F572945706Q26852989-7A9E88A8-9541-4406-B986-686D03425FF9Q27005597-40B38DB2-9A4E-4886-BFAA-50B24A353066Q27010574-832A7C2C-FAB2-4BDC-979D-D4C7B7431FD0Q27300989-C98A660A-A839-48E7-96D2-39ECE4B8FF37Q27323458-AFFB3475-FB5C-4666-BA09-5B3F01F0A034Q28083324-367AC944-B436-4DA5-B7F2-B0A3D6DE339FQ30152836-AF9959AA-EA79-4C3B-8CAE-67231CD5C9D7Q30837462-3EC0362E-5C85-4A5D-B344-60F1C5D6610BQ30843477-033E7EDB-97E1-41F2-9C98-14D8D632E4A9Q34440312-9A8B02E1-1014-42EF-B8CB-CD4F492AC7D5Q35034401-6184CE6A-666A-41C0-BB1F-95C77B1926D4Q35121258-810EF152-A6C3-4A2C-9E1A-127F1A900084Q35153080-BE1A7FD1-BD8B-403A-AD1D-D1399E8FE89BQ35340196-7A213291-A93A-4FE2-B623-61C46EBCB301Q35651062-80854E26-3F8D-4391-BA71-CAC1B23F462CQ35848706-E47BE91D-0884-49FB-AF8D-33E55BE698FCQ35853990-7D8ED492-2B28-41D1-832A-7D0B740FFCB1Q35999976-E7A5418C-C1FB-4544-B96A-48F06BEFBF66Q36006011-E0839BFA-3827-4494-9560-EC3B2514672FQ36106403-F706ED4B-CF9E-49CB-B4E5-B7A028CEB36CQ36270392-4615CF1D-D927-438E-9322-09FA55B10F2FQ36349980-44C2FE54-0618-4570-A295-ADB21570D6F2Q36352399-8620EF3C-C4D2-4DFB-AD4A-933D5537E1D8Q36482816-0CFB7C23-AE45-4576-AEB1-C08AE93CA8A3Q36649689-C7691E88-F294-43D0-A7B0-C2DED716A80FQ36756879-2B9C6D23-61FE-4C29-8F9C-0DC170D4D155Q36757186-9F4014C3-30E4-4211-AFD9-25C4740A89DEQ36951265-CE48F3F7-1251-4529-8B32-9032CB32D6E3Q37043518-226624E1-43A4-4521-A963-D0E1C8A9C016Q37127238-9E1D580D-BCF0-4CB7-9978-3FB9547E5A08Q37265779-29DA8EA0-66B8-49CE-B2C3-D3F09400FC1BQ37277317-8C52A50F-3E9C-406B-B3B7-98375273B561Q37351327-52F344E9-B770-4835-8288-539FDF96B069Q37393559-DD1850D5-E0DE-422F-9FE6-A772EF2DFB50Q37481531-3C0761C5-031F-482C-9029-A386753011DFQ37571229-6B623DF0-45BB-438B-9A3D-2D5AC633E4F5Q38310488-3132D7D3-C342-43A6-B9EC-B94D09E09C5B
P2860
Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@ast
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@en
type
label
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@ast
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@en
prefLabel
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@ast
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@en
P2093
P2860
P356
P1433
P1476
Global CNS transduction of adu ...... nonhuman primates by rAAVrh.10
@en
P2093
Chunyan Cao
Dominic J Gessler
Guangping Gao
Hongwei Zhang
Hongyan Wang
Joshua Kramer
P2860
P304
P356
10.1038/MT.2014.68
P577
2014-04-30T00:00:00Z