Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function - Wikidata - awgldk - TriplyDB

Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

http://www.wikidata.org/entity/Q33873546

about

Tumor and stromal-based contributions to head and neck squamous cell carcinoma invasion Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence Spatiotemporal regulation of Src and its substrates at invadosomes Multi-photon imaging of tumor cell invasion in an orthotopic mouse model of oral squamous cell carcinoma Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas.High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis.Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells.Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.Impact of flavonoids on matrix metalloproteinase secretion and invadopodia formation in highly invasive A431-III cancer cells STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma Distinct effects of saracatinib on memory CD8+ T cell differentiation.Src-signaling interference impairs the dissemination of blood-borne tumor cells MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma Src binds cortactin through an SH2 domain cystine-mediated linkage.Dasatinib Inhibits DNA Repair after Radiotherapy Specifically in pSFK-Expressing Tumor Areas in Head and Neck Xenograft Tumors.Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop.Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis.Autophagic action of new targeting agents in head and neck oncology.Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance Quantitative measurement of invadopodia-mediated extracellular matrix proteolysis in single and multicellular contexts.Invadosomes are coming: new insights into function and disease relevance.Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.Drugs for solid cancer: the productivity crisis prompts a rethink.Effectiveness of inhibitor rapamycin, saracatinib, linsitinib and JNJ-38877605 against human prostate cancer cells.Revisiting the ERK/Src cortactin switch Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases.Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib.

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Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

http://www.wikidata.org/entity/Q33873546

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

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2009年論文

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2009年論文

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2009年论文

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Saracatinib Impairs Head and N ...... isrupting Invadopodia Function

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Saracatinib Impairs Head and N ...... isrupting Invadopodia Function

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Saracatinib Impairs Head and N ...... isrupting Invadopodia Function

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Saracatinib Impairs Head and N ...... isrupting Invadopodia Function

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1948-5956.1000009

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Journal of cancer science & therapy

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Saracatinib Impairs Head and N ...... isrupting Invadopodia Function

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Amanda Gatesman Ammer

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Barbara Frederick

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Brian L Rothschild

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David Raben

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Jason V Evans

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Karen E Hayes

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Karen H Martin

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Laura C Kelley

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Lesly Ann Lopez-Skinner

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Paul Elvin

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P2860

Src family kinases in tumor progression and metastasis

Newest findings on the oldest oncogene; how activated src does it

Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1

Cortactin branches out: roles in regulating protrusive actin dynamics

Differential regulation of cell motility and invasion by FAK

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Invadopodia: specialized cell structures for cancer invasion

Assembly and biological role of podosomes and invadopodia

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

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52-61

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20505783

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