The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18.
about
LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidenceCrystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interactionStructural basis for NKG2A/CD94 recognition of HLA-E.Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptorHuman inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-GImmune regulation of human herpesviruses and its implications for human transplantationThe CD200-CD200R1 inhibitory signaling pathway: immune regulation and host-pathogen interactionsHLA-dependent tumour development: a role for tumour associate macrophages?Molecular Recognition of Paired Receptors in the Immune SystemCrystal structure of the murine NK cell-activating receptor NKG2D at 1.95 ACrystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptorCrystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptorsThe Crystal Structure of CHIR-AB1: A Primordial Avian Classical Fc ReceptorStructure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptorThe Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound PeptideCrystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k): A MYELOID INHIBITORY RECEPTOR INVOLVED IN IMMUNE TOLERANCECrystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA bindingThe structure of cytomegalovirus immune modulator UL141 highlights structural Ig-fold versatility for receptor bindingFunctional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptorsHydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteinsLymphocyte cell-cycle inhibition by HLA-G is mediated by phosphatase SHP-2 and acts on the mTOR pathwayHerpesviral capture of immunomodulatory host genes.Microbial manipulation of receptor crosstalk in innate immunityHuman cytomegalovirus UL18 utilizes US6 for evading the NK and T-cell responsesThe human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.A potential role for shed soluble major histocompatibility class I molecules as modulators of neurite outgrowth.Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface.Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cellsUL40-mediated NK evasion during productive infection with human cytomegalovirus.HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.Comparative genomic analysis of the MHC: the evolution of class I duplication blocks, diversity and complexity from shark to man.Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state.Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas diseaseThe LILR family: modulators of innate and adaptive immune pathways in health and disease.Human natural killer cell receptors and signal transduction.Fc receptor homologs: newest members of a remarkably diverse Fc receptor gene family.How the virus outsmarts the host: function and structure of cytomegalovirus MHC-I-like molecules in the evasion of natural killer cell surveillance
P2860
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P2860
The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@ast
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@en
type
label
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@ast
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@en
prefLabel
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@ast
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@en
P2093
P1433
P1476
The inhibitory receptor LIR-1 ...... es and the viral homolog UL18.
@en
P2093
Bjorkman PJ
Chapman TL
Heikeman AP
P304
P356
10.1016/S1074-7613(00)80135-1
P407
P577
1999-11-01T00:00:00Z