The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
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Hepcidin: A Promising Therapeutic Target for Iron Disorders: A Systematic ReviewMurine mutants in the study of systemic iron metabolism and its disorders: an update on recent advancesIron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levelsIron regulation by hepcidinmRNA regulation of cardiac iron transporters and ferritin subunits in a mouse model of iron overloadLiver and muscle hemojuvelin are differently glycosylated.Transferrin is a major determinant of hepcidin expression in hypotransferrinemic miceIncreased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway.Low intracellular iron increases the stability of matriptase-2.Hereditary hemochromatosis and transferrin receptor 2Chronic inflammation and iron metabolism.The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro.Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy.Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage.Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.Vitamin A deficiency modulates iron metabolism independent of hemojuvelin (Hfe2) and bone morphogenetic protein 6 (Bmp6) transcript levels.A late presentation of a fatal disease: juvenile hemochromatosis.Iron homeostasis in the liver.Sex differences and steroid modulation of cardiac iron in a mouse model of iron overload.Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis.Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling.Iron age: novel targets for iron overload.Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.Soluble hemojuvelin in transfused and untransfused thalassaemic subjects.Sox2 function as a negative regulator to control HAMP expression.Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in miceIron overload induces BMP6 expression in the liver but not in the duodenum.Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway.Ineffective Erythropoiesis: Anemia and Iron Overload.Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.Effect of pH on the stability of hemochromatosis factor E: a combined spectroscopic and molecular dynamics simulation-based study.Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.
P2860
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P2860
The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@ast
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@en
type
label
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@ast
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@en
prefLabel
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@ast
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@en
P2093
P2860
P356
P1476
The role of hepatocyte hemojuv ...... d hepcidin expression in vivo.
@en
P2093
An-Sheng Zhang
Caroline A Enns
Dwight D Koeberl
Junwei Gao
P2860
P304
16416-16423
P356
10.1074/JBC.M110.109488
P407
P577
2010-04-02T00:00:00Z