Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294. - Wikidata - awgldk - TriplyDB

Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

http://www.wikidata.org/entity/Q33883423

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Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells Epigenetic control of HIV-1 post integration latency: implications for therapy Impact of Chromatin on HIV Replication Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus Chemical probes of histone lysine methyltransferases HIV-1 functional cure: will the dream come true?Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure Chemical probes targeting epigenetic proteins: Applications beyond oncology.The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1 HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection.The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit.Interaction between endogenous bacterial flora and latent HIV infection.Gene silencing in HIV-1 latency by polycomb repressive group.HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research Viral-host interactions that control HIV-1 transcriptional elongation Selective inhibitors of protein methyltransferases Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines Down-regulation of G9a triggers DNA damage response and inhibits colorectal cancer cells proliferation.Blimp-1, an intrinsic factor that represses HIV-1 proviral transcription in memory CD4+ T cells.The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells.The mTOR Complex Controls HIV Latency.Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1.G9a, a multipotent regulator of gene expression.HIV latency: experimental systems and molecular models.Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage.Targeting HIV latency: pharmacologic strategies toward eradication.Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector Ixodes scapularis.HIV-1 transcription and latency: an update.Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs Epigenetics, drugs of abuse, and the retroviral promoter.Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.HIV-1 Latency and Eradication: Past, Present and Future Epigenetic regulation of HIV-1 latency in astrocytes Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.

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Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

http://www.wikidata.org/entity/Q33883423

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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type

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Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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prefLabel

Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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Involvement of histone H3 lysi ...... its reactivation by BIX01294.

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JBC.M110.103531

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Journal of Biological Chemistry

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Involvement of histone H3 lysi ...... its reactivation by BIX01294.

@en

P2093

Hiroaki Togami

http://www.w3.org/2001/XMLSchema#string

Kenichi Imai

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Takashi Okamoto

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P2860

Translating the Histone Code

Crystal structure of the nucleosome core particle at 2.8 A resolution

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

Transcriptional repression of human immunodeficiency virus type 1 by AP-4

The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1.

CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

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285

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2010-03-24T00:00:00Z

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