Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation
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Dopamine-induced α-synuclein oligomers show self- and cross-propagation properties.Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic aβ peptide aggregatesGadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease.Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation.Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environmentsDetermination of critical nucleation number for a single nucleation amyloid-β aggregation model.Conformational Dynamics of Specific Aβ Oligomers Govern Their Ability To Replicate and Induce Neuronal ApoptosisStrain-specific Fibril Propagation by an Aβ Dodecamer.The natural product betulinic acid rapidly promotes amyloid-β fibril formation at the expense of soluble oligomers.Fatty Acid Concentration and Phase Transitions Modulate Aβ Aggregation Pathways.Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions.Do astrocytes collaborate with neurons in spreading the "infectious" aβ and Tau drivers of Alzheimer's disease?Propagation of an Aβ Dodecamer Strain Involves a Three-Step Mechanism and a Key Intermediate.Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases
P2860
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P2860
Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Non-esterified fatty acids gen ...... ifferent from fibril formation
@ast
Non-esterified fatty acids gen ...... ifferent from fibril formation
@en
type
label
Non-esterified fatty acids gen ...... ifferent from fibril formation
@ast
Non-esterified fatty acids gen ...... ifferent from fibril formation
@en
prefLabel
Non-esterified fatty acids gen ...... ifferent from fibril formation
@ast
Non-esterified fatty acids gen ...... ifferent from fibril formation
@en
P2093
P2860
P1433
P1476
Non-esterified fatty acids gen ...... ifferent from fibril formation
@en
P2093
Dipti Singh
Lea C Paslay
Pritesh Patel
Rebekah L Bullard
Sarah E Morgan
Vijayaraghavan Rangachari
P2860
P304
P356
10.1371/JOURNAL.PONE.0018759
P407
P577
2011-04-19T00:00:00Z