NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
about
The Notch signaling regulates CD105 expression, osteogenic differentiation and immunomodulation of human umbilical cord mesenchymal stem cellsPhosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsImmune targeting of cancer stem cells in gastrointestinal oncologyGlioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsCancer stem cells: a metastasizing menace!Targeting Notch to overcome radiation resistanceIonizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological CancersTargeting cancer stem cells by using the nanoparticlesTargeting Aggressive Cancer Stem Cells in GlioblastomaTwisted tango: brain tumor neurovascular interactionsTargeting the Notch signaling pathway in cancer therapeuticsBrain tumor stem cells: Molecular characteristics and their impact on therapyThe potential origin of glioblastoma initiating cellsNovel delivery strategies for glioblastomaCancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer TreatmentTargeting glioma stem cells: a novel framework for brain tumorsPericytes, an overlooked player in vascular pathobiologyNotch signalling pathway as an oncogenic factor involved in cancer developmentIn vitro models of cancer stem cells and clinical applicationsEMT, CTCs and CSCs in tumor relapse and drug-resistanceProtein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung AdenocarcinomaSustained proliferation in cancer: Mechanisms and novel therapeutic targetsZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell statePigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.Notch inhibition as a promising new approach to cancer therapy.The role of microRNAs in glioma initiation and progression.EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinaseMotility of glioblastoma cells is driven by netrin-1 induced gain of stemnessA patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.More than markers: biological significance of cancer stem cell-defining molecules.Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma.Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells.Identification of cell surface glycoprotein markers for glioblastoma-derived stem-like cells using a lectin microarray and LC-MS/MS approach.γ-secretase inhibitor DAPT sensitizes t-AUCB-induced apoptosis of human glioblastoma cells in vitro via blocking the p38 MAPK/MAPKAPK2/Hsp27 pathwaySTAT3 serine 727 phosphorylation influences clinical outcome in glioblastoma.Wnt activation promotes neuronal differentiation of glioblastomaInhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signatureThe top cited articles on glioma stem cells in Web of SciencePotential therapeutic implications of cancer stem cells in glioblastoma
P2860
Q23922359-6A2D5A50-AF50-494B-85E5-05481805E66AQ24293124-67EC8B16-44B9-448A-AC79-FA7D90DF08ADQ26749015-79F5D041-9299-4399-B8B0-BFD386A7AB7DQ26765758-1C86CA91-1E40-4C6F-9762-AB8AF8847B42Q26771651-08FFF59C-A253-4A15-B811-684D0F6FD34DQ26771701-7FFB8A7D-C061-4D51-AC26-7DCD680B8E40Q26777120-59E75841-781D-4FAA-B37D-448ACE35BC72Q26783590-DC80AFF1-68F8-4387-BD6A-2A317E5FFABBQ26799983-26DBA705-CAC6-4ADD-BCB1-FCDF6FC4810CQ26849613-D0D55644-5784-4F72-B917-610168E6DC06Q26863580-F8BE94C3-445A-4E61-9D55-C9BE5EF61974Q27003138-E7661808-80C3-4B82-AF79-CDAD3B4FBDF8Q27005807-560BFD58-26F4-4814-8A7E-AFA233E1163FQ27006099-CC0792A4-A946-4501-B546-FD3E88CF78BBQ27024816-067191DB-3558-4520-BF55-3254AB8704E9Q27026818-B12F48F6-BC22-4674-B56A-651A08A87E68Q28070053-22993EBC-42D4-4686-82EA-C71B573DDA4FQ28072977-FF97B631-5E8B-49F9-9860-4D9244AD694BQ28076101-58370189-D4D2-43C7-ACF0-ABCB3437FD53Q28082935-6A465540-FFEE-4575-A92A-C310A5D972DAQ28115044-49701E62-A0A6-4A21-9AF0-7D5B1F7A3151Q28396388-6C84CF4F-0186-4B3C-8262-99FFFDF343E2Q28594320-CB53ECEA-D4C0-43B8-84B8-5F517EE07EC4Q30393905-E89ABD8F-1543-49CC-85DD-F5F57D2E0BF9Q30426785-8980398D-DFCF-4A35-90A3-E4544314A4B6Q30428370-EE0D5246-CA27-436E-8729-E270241AD26CQ30514025-89B4481B-2871-44C7-9AF4-978BB9FC86B1Q30834482-0C68B075-0A7D-4208-AD9F-25C95E338D7DQ33616598-4382FAF5-B8B0-4DDD-A04E-AD741F219204Q33661278-7977E74B-0685-41AA-9668-01117E92BA1BQ33753468-967DE2EC-E9C3-4200-8BC6-EA1019950AFEQ33779353-7A7B4CB5-36A0-4296-B572-9EC871C6719FQ33779474-7325B776-15E8-4F08-AA41-E13CC05AC60FQ33835228-DF16EE85-B449-430A-A6F3-8633EA7E0B3CQ33861921-D68E6099-F39B-42F2-BB1A-DC7086AE8FD8Q33898587-E4526548-81E7-4B7C-B8AF-89AFDAA9A611Q33903166-8A3DC4B5-298B-46D2-B6DD-7B54899A9E20Q33911184-A0C69C3E-6C90-4EB5-AE44-1975F9271332Q33937611-C6BE0020-67E3-42CC-8816-1F11D17D64BBQ33965491-30D2DE84-DF9E-4E36-A126-6A17C75B5842
P2860
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@ast
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@en
type
label
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@ast
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@en
prefLabel
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@ast
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@en
P2093
P2860
P50
P356
P1433
P1476
NOTCH pathway blockade deplete ...... or neurospheres and xenografts
@en
P2093
Caroline E Talsma
Cheryl Koh
Guido Nikkhah
Jarek Maciaczyk
Leila Khaki
Mary E Soules
Naheed Gul
Thant S Zhu
Yue-Ming Li
P2860
P356
10.1002/STEM.254
P577
2010-01-01T00:00:00Z