Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response - Wikidata - awgldk - TriplyDB

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

http://www.wikidata.org/entity/Q33886159

about

In Hot Pursuit of the First Vaccine Against Respiratory Syncytial Virus Biomarkers of respiratory syncytial virus (RSV) infection: specific neutrophil and cytokine levels provide increased accuracy in predicting disease severity Modulation of host adaptive immunity by hRSV proteins The non-structural NS1 protein unique to respiratory syncytial virus: a two-state folding monomer in quasi-equilibrium with a stable spherical oligomer RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo The interactome of the human respiratory syncytial virus NS1 protein highlights multiple effects on host cell biology Differentiation of Th subsets inhibited by nonstructural proteins of respiratory syncytial virus is mediated by ubiquitination.Tick-borne flaviviruses antagonize both IRF-1 and type I IFN signaling to inhibit dendritic cell function.Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells.Differential impact of respiratory syncytial virus and parainfluenza virus on the frequency of acute otitis media is explained by lower adaptive and innate immune responses in otitis-prone children.A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes Antiviral B cell and T cell immunity in the lungs.Protective and dysregulated T cell immunity in RSV infection Subtypes of type I IFN differentially enhance cytokine expression by suboptimally stimulated CD4(+) T cells.A gene expression signature for RSV: clinical implications and limitations.An overview of respiratory syncytial virus.Paramyxovirus infection regulates T cell responses by BDCA-1+ and BDCA-3+ myeloid dendritic cells.Viruses, autophagy genes, and Crohn's disease.Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years Immunological, Viral, Environmental, and Individual Factors Modulating Lung Immune Response to Respiratory Syncytial Virus.The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.Prenatal Exposure to Respiratory Syncytial Virus Alters Postnatal Immunity and Airway Smooth Muscle Contractility during Early-Life Reinfections Preexposure to CpG protects against the delayed effects of neonatal respiratory syncytial virus infection.Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice Neutrophil in viral infections, friend or foe?Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice.Human respiratory syncytial virus non-structural protein NS1 modifies miR-24 expression via transforming growth factor-β.Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration.Differential response of BDCA-1+ and BDCA-3+ myeloid dendritic cells to respiratory syncytial virus infection Virus infection facilitates the development of severe pneumonia in transplant patients with hematologic malignancies.Attenuated Bordetella pertussis vaccine protects against respiratory syncytial virus disease via an IL-17-dependent mechanism.Respiratory syncytial virus infection and immunity.The role of dendritic cells in innate and adaptive immunity to respiratory syncytial virus, and implications for vaccine development.Central nervous system alterations caused by infection with the human respiratory syncytial virus.New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus.Viral manipulation of the host immune response.Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus.Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection.Modulation of the host immune response by respiratory syncytial virus proteins.

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Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

http://www.wikidata.org/entity/Q33886159

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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Respiratory syncytial virus in ...... he human T lymphocyte response

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Alexander Bukreyev

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Cyril Le Nouën

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Peter L Collins

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Philippa Hillyer

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Ronald L Rabin

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Shirin Munir

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Ursula J Buchholz

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P2860

Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

Interleukin-17 family members and inflammation

Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

Phenotypic and functional features of human Th17 cells

T-cell quality in memory and protection: implications for vaccine design

Perforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand.

Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection.

Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines.

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Cyril Le Nouën

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51089266

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