The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53.
about
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersRole for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycleMitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylationPhosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phaseDisruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell divisionCharacterization of the Net1 cell cycle-dependent regulator of the Cdc14 phosphatase from budding yeast.Pathway connectivity and signaling coordination in the yeast stress-activated signaling network.Diabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testisStoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription.Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressThe CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryoFunctional redundancy between Cdc14 phosphatases in zebrafish ciliogenesis.Functional homology among human and fission yeast Cdc14 phosphatases.Functional analysis of the Fusarium graminearum phosphatome.Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression.Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication.Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infectionOncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1.Genome editing through large insertion leads to the skipping of targeted exonModulator of apoptosis 1 (MOAP-1) is a tumor suppressor protein linked to the RASSF1A protein.Opposing post-translational modifications regulate Cep76 function to suppress centriole amplification.Regulation of p53--insights into a complex process.Molecular mechanisms of the PRL phosphatases.Inhibition of miR-630 enhances the cell resistance to radiation by directly targeting CDC14A in human gliomaPhospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression.Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner.Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315.Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology.C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis.Activation of p53 by roscovitine-mediated suppression of MDM2 expression.Kinetic and mechanistic studies of a cell cycle protein phosphatase Cdc14.Clonal heterogeneity of mantle cell lymphoma revealed by array comparative genomic hybridization.CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human.IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
P2860
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P2860
The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53.
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2000 թվականի հունվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@ast
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@en
type
label
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@ast
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@en
prefLabel
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@ast
The human Cdc14 phosphatases i ...... tumor suppressor protein p53.
@en
P2860
P356
P1476
The human Cdc14 phosphatases i ...... e tumor suppressor protein p53
@en
P2093
P2860
P304
P356
10.1074/JBC.275.4.2410
P407
P50
P577
2000-01-01T00:00:00Z