Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking. - Wikidata - awgldk - TriplyDB

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.

http://www.wikidata.org/entity/Q33887759

about

HIVToolbox, an integrated web application for investigating HIV DNA binding induces dissociation of the multimeric form of HIV-1 integrase: a time-resolved fluorescence anisotropy study Retroviral intasome assembly and inhibition of DNA strand transfer Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.Phosphate coordination and movement of DNA in the Tn5 synaptic complex: role of the (R)YREK motif Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes.Determinants for hairpin formation in Tn10 transposition.Identification of a nucleotide binding site in HIV-1 integrase Localization of ASV integrase-DNA contacts by site-directed crosslinking and their structural analysis Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics Insertion sequences Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis Structural determinants of metal-induced conformational changes in HIV-1 integrase.Soluble expression, purification and characterization of the full length IS2 Transposase.Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor Self-association and domains of interactions of an amphipathic helix peptide inhibitor of HIV-1 integrase assessed by analytical ultracentrifugation and NMR experiments in trifluoroethanol/H(2)O mixtures.Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence.Asymmetric photocross-linking pattern of restriction endonuclease EcoRII to the DNA recognition sequence.Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase.Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody.An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding Predicting protein-DNA interactions by full search computational docking.A dynamic model of HIV integrase inhibition and drug resistance.Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase.The HIV-1 integrase α4-helix involved in LTR-DNA recognition is also a highly antigenic peptide element HIV-1 IN inhibitors: 2010 update and perspectives A family of developmentally excised DNA elements in Tetrahymena is under selective pressure to maintain an open reading frame encoding an integrase-like protein Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction.Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome Characterization of insertions of IS476 and two newly identified insertion sequences, IS1478 and IS1479, in Xanthomonas campestris pv. campestris Developing G-quartet oligonucleotides as novel anti-HIV agents: focus on anti-HIV drug design.Tipping the balance between replicative and simple transposition

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Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.

http://www.wikidata.org/entity/Q33887759

description

1997 nî lūn-bûn

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1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի նոյեմբերին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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The EMBO Journal

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Critical contacts between HIV- ...... alysis and photo-crosslinking.

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A Engelman

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D Esposito

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R Craigie

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T M Jenkins

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P2860

DNA sequencing with chain-terminating inhibitors

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

Solution structure of the DNA binding domain of HIV-1 integrase

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

The DNA-binding domain of HIV-1 integrase has an SH3-like fold.

Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

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6849-6859

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scholarly article

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22

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16

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1997-11-01T00:00:00Z

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9362498

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1170288

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