Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.
about
Agonist binding by the β2-adrenergic receptor: an effect of receptor conformation on ligand association-dissociation characteristicsGi proteins regulate adenylyl cyclase activity independent of receptor activationBiased β2-adrenoceptor signalling in heart failure: pathophysiology and drug discovery.Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β2-adrenoceptorBiased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and PathologyGPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells.The N-terminus of the yeast G protein-coupled receptor Ste2p plays critical roles in surface expression, signaling, and negative regulation.Stereoselective binding of agonists to the β2-adrenergic receptor: insights into molecular details and thermodynamics from molecular dynamics simulations.Challenges and Opportunities in Drug Discovery of Biased Ligands.Correspondence: Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury.Ligand-induced action of the W2866.48 rotamer toggle switch in the β2-adrenergic receptor.ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure
P2860
Q35176476-EE07B179-35CB-4DC1-A1C2-C837901452C6Q35244302-12D89A7A-C96A-4D8F-BC7D-43F00D48BD35Q36342091-92EAF2D2-2446-470E-A69A-8AECA00626EFQ36342155-AEE8ABA9-E9F7-478F-9190-C68104314346Q37551908-569114AD-AFB4-45EB-81C9-A18A367B24FFQ38662813-15381A67-4D23-4FDA-B309-FA9D085F8E9CQ38675922-513FE6BF-EE9B-46F7-B74F-E637448AECBEQ38791090-04FC0F2A-C4DE-4647-A89A-A9F1E6324EB4Q38798242-2A46C5DB-9BD2-479B-AAC3-664BF079E65BQ38880205-CE76E912-0D3C-4322-8A2D-725FF9E2950DQ47348665-70A79772-E4E0-4AA9-9A45-64CC4F151D3CQ49540694-EC4909D2-EC43-4714-8363-C17CC3C18885Q49957864-43C9DEB8-B0C9-46A2-A9F4-CD5BFB5C5A7DQ58119331-8E393C20-2792-48CF-9EB8-9243816A055E
P2860
Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@ast
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@en
type
label
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@ast
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@en
prefLabel
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@ast
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@en
P2093
P2860
P50
P356
P1476
Tyrosine 308 is necessary for ...... signaling of β2-adrenoceptor.
@en
P2093
Irving W Wainer
Joseph A Kozocas
Karolina Pajak
Lawrence Toll
Lucita Jimenez
Mary J Tanga
Rajib K Paul
Rui-Ping Xiao
Ying Huang
P2860
P304
19351-19363
P356
10.1074/JBC.M114.558882
P407
P577
2014-05-15T00:00:00Z