Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

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http://www.wikidata.org/entity/Q33888534
Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de MeledaEvidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1).Structural Analysis and Deletion Mutagenesis Define Regions of QUIVER/SLEEPLESS that Are Responsible for Interactions with Shaker-Type Potassium Channels and Nicotinic Acetylcholine Receptors.The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.Chylomicronaemia--current diagnosis and future therapies.Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries.An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.GPIHBP1 and Plasma Triglyceride Metabolism.GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding.Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.Lipoprotein lipase reaches the capillary lumen in chickens despite an apparent absence of GPIHBP1.GPIHBP1: two get tangled.Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum.
P2860

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

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http://www.wikidata.org/entity/Q33888534
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2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@ast
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@en
type
label
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@ast
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@en
prefLabel
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@ast
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Multimerization of glycosylpho ...... titution in GPIHBP1 Ly6 domain
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932