The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery
about
PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importMembers of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptorThe Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membraneUbiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import.Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteinsUbiquitination of the peroxisomal import receptor Pex5p is required for its recyclingThe Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells.Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down.Peroxisomal remnant structures in Hansenula polymorpha Pex5 cells can develop into normal peroxisomes upon induction of the PTS2 protein amine oxidase.How peroxisomes arise.The life cycle of the peroxisome.Protein translocation machineries of peroxisomes.Identification of six loci in which mutations partially restore peroxisome biogenesis and/or alleviate the metabolic defect of pex2 mutants in podospora.Peroxisome biogenesis and the role of protein import.Elevated growth temperature decreases levels of the PEX5 peroxisome-targeting signal receptor and ameliorates defects of Arabidopsis mutants with an impaired PEX4 ubiquitin-conjugating enzyme.Characterization of glycosomal RING finger proteins of trypanosomatids.Dynamics of the peroxisomal import cycle of PpPex20p: ubiquitin-dependent localization and regulation.The peroxisomal protein import machinery.Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes.Peroxisome-associated matrix protein degradation in Arabidopsis.Shuttles and cycles: transport of proteins into the peroxisome matrix (review).The exportomer: the peroxisomal receptor export machinery.Normal peroxisome development from vesicles induced by truncated Hansenula polymorpha Pex3p.Overproduction of Pex5p stimulates import of alcohol oxidase and dihydroxyacetone synthase in a Hansenula polymorpha Pex14 null mutant.A stretch of positively charged amino acids at the N terminus of Hansenula polymorpha Pex3p is involved in incorporation of the protein into the peroxisomal membrane.Identification and functional characterization of Arabidopsis PEROXIN4 and the interacting protein PEROXIN22.The peroxisome biogenesis factors pex4p, pex22p, pex1p, and pex6p act in the terminal steps of peroxisomal matrix protein import.Ubiquitination of the peroxisomal import receptor Pex5pHansenula polymorpha Pex3p is a peripheral component of the peroxisomal membrane.A novel method to determine the topology of peroxisomal membrane proteins in vivo using the tobacco etch virus protease.Hansenula polymorpha Pex1p and Pex6p are peroxisome-associated AAA proteins that functionally and physically interact.Antibodies against pex14p block ATP-independent binding of matrix proteins to peroxisomes in vitro.
P2860
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P2860
The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@ast
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@en
type
label
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@ast
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@en
prefLabel
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@ast
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@en
P2093
P2860
P356
P1433
P1476
The ubiquitin-conjugating enzy ...... g of the PTS1 import machinery
@en
P2093
Hilbrands RE
Rasmussen SW
Veenhuis M
van der Klei IJ
P2860
P304
P356
10.1093/EMBOJ/17.13.3608
P407
P577
1998-07-01T00:00:00Z