A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription
about
TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3pMultiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoterhRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promotersMultiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcriptionmTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityCasein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcriptionRNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and humanBasic mechanisms in RNA polymerase I transcription of the ribosomal RNA genesRNA polymerase I-Rrn3 complex at 4.8 Å resolution.Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growthRNA polymerase I structure and transcription regulationAn alternative RNA polymerase I structure reveals a dimer hingeThe transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively.CTD kinase I is involved in RNA polymerase I transcriptionRpa43 and its partners in the yeast RNA polymerase I transcription complex.DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription.Partners of Rpb8p, a small subunit shared by yeast RNA polymerases I, II and IIITOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA productionGenetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcriptionCcr4-not regulates RNA polymerase I transcription and couples nutrient signaling to the control of ribosomal RNA biogenesisRPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase.In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes.Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast.Tor pathway regulates Rrn3p-dependent recruitment of yeast RNA polymerase I to the promoter but does not participate in alteration of the number of active genes.Differential protein expression following low temperature culture of suspension CHO-K1 cellsSurvey and summary: transcription by RNA polymerases I and III.Structural mechanism of ATP-independent transcription initiation by RNA polymerase IDifferential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.Nucleolar dominance and ribosomal RNA gene silencingLocalization of the yeast RNA polymerase I-specific subunits.The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits.UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat.Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae.UBF activates RNA polymerase I transcription by stimulating promoter escape.The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components.
P2860
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P2860
A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A specialized form of RNA poly ...... disrupted during transcription
@ast
A specialized form of RNA poly ...... disrupted during transcription
@en
type
label
A specialized form of RNA poly ...... disrupted during transcription
@ast
A specialized form of RNA poly ...... disrupted during transcription
@en
prefLabel
A specialized form of RNA poly ...... disrupted during transcription
@ast
A specialized form of RNA poly ...... disrupted during transcription
@en
P2860
P356
P1433
P1476
A specialized form of RNA poly ...... disrupted during transcription
@en
P2093
H Tschochner
P Milkereit
P2860
P304
P356
10.1093/EMBOJ/17.13.3692
P407
P577
1998-07-01T00:00:00Z