Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion
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Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organizationVinculin regulates cell-surface E-cadherin expression by binding to beta-cateninKIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomasalpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsRecruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesionIdentification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.Vinculin and metavinculin: oligomerization and interactions with F-actinThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationVinculin controls talin engagement with the actomyosin machinery.Schwann cells promote endothelial cell migrationTalin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.Vinculin controls focal adhesion formation by direct interactions with talin and actin.Erk1/2 MAPK and caldesmon differentially regulate podosome dynamics in A7r5 vascular smooth muscle cells.Vinculin is a dually regulated actin filament barbed end-capping and side-binding proteinVisualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor.Drosophila integrin adhesion complexes are essential for hemocyte migration in vivo.Cleavage of E-cadherin and β-catenin by calpain affects Wnt signaling and spheroid formation in suspension cultures of human pluripotent stem cellsCooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.Differences in F9 and 5.51 cell elasticity determined by cell poking and atomic force microscopy.Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity.Embryonic stem cell models of development.Vinculin facilitates cell invasion into three-dimensional collagen matrices.Talin contains three similar vinculin-binding sites predicted to form an amphipathic helixCell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assemblyMesenchymal migration as a therapeutic target in glioblastoma.A molecular dynamics investigation of vinculin activation.Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo.Comparative biochemical analysis suggests that vinculin and metavinculin cooperate in muscular adhesion sites.Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancerDown-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cellsVinculin activators target integrins from within the cell to increase melanoma sensitivity to chemotherapy.Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathyNew insights into vinculin function and regulation.The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties.Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.Inositol 1, 4, 5-trisphosphate-dependent nuclear calcium signals regulate angiogenesis and cell motility in triple negative breast cancer.The lipoxygenase inhibitor, baicalein, modulates cell adhesion and migration by up-regulation of integrins and vinculin in rat heart endothelial cellsSignaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.Mechano-coupling and regulation of contractility by the vinculin tail domain
P2860
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P2860
Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@ast
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@en
type
label
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@ast
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@en
prefLabel
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@ast
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@en
P2093
P2860
P356
P1476
Targeted disruption of vinculi ...... logy, adhesion, and locomotion
@en
P2093
E D Adamson
H Baribault
J L Rodríguez Fernández
R G Oshima
R M Ezzell
P2860
P304
P356
10.1073/PNAS.92.20.9161
P407
P577
1995-09-01T00:00:00Z