Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.
about
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogsATP-binding cassette (ABC) transporters in normal and pathological lungMultidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical applicationBilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1)Functional and genetic analysis of choroid plexus development in zebrafish.Expression of HNF4alpha in the human and rat choroid plexus: implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrierXenobiotic, bile acid, and cholesterol transporters: function and regulation.Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat.Blood-brain barrier active efflux transporters: ATP-binding cassette gene family.A family of drug transporters: the multidrug resistance-associated proteins.Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus.Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in miceMultidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.ABC multidrug transporters: structure, function and role in chemoresistance.Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria.The role of drug efflux pumps in acute myeloid leukemia.In vitro, in vivo and ex vivo characterization of ibrutinib: a potent inhibitor of the efflux function of the transporter MRP1.ABC transporters: unvalidated therapeutic targets in cancer and the CNSHuman pharmacogenomic variations and their implications for antifungal efficacy.Development and characterization of transgenic mouse models for conditional gene knockout in the blood-brain and blood-CSF barriers.The MRP family of drug efflux pumps.Bilirubin, a curse and a boon.Choroid plexus transport: gene deletion studies.Clinical relevance of P-glycoprotein in drug therapy.A review of selected anti-tumour therapeutic agents and reasons for multidrug resistance occurrence.Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.Modulation of p-glycoprotein transport function at the blood-brain barrier.Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.Role of ABC transporters in the pathogenesis of Alzheimer's diseaseTransmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Use of in vitro transporter assays to understand hepatic and renal disposition of new drug candidates.Blood-brain barrier and chemotherapeutic treatment of brain tumors.The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects.Chalcogenopyrylium dyes as differential modulators of organic anion transport by multidrug resistance protein 1 (MRP1), MRP2, and MRP4Xenobiotic transporters: ascribing function from gene knockout and mutation studies.PET and SPECT radiotracers to assess function and expression of ABC transporters in vivoDevelopment of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection
P2860
Q24681283-5C05E8EB-6889-48C9-A8D5-92C13A2600BFQ24811895-7BE531FF-5830-4913-9AC6-D06EF3E06F05Q28468693-EEA805AA-7CCA-4AC5-BEC5-77E34EE56C4CQ30535334-03D2A9D2-F835-4D2C-8952-F532E9A5BA6FQ30597227-D6273283-0AE0-445F-853B-3A1445CFFB82Q33478002-611C4C2A-40BD-4073-AFCD-407350B0F759Q33714593-4E1DD99A-BC09-470F-9212-630AA59E41BAQ33812983-6AE0CCDC-E6EA-42A8-A711-899548D8478FQ33985133-628DB591-3513-4AD6-AAA4-6FFE8F54D5F0Q34004952-1BAB4208-1FD5-48A5-B9C0-C22EFE2F6E8FQ34116952-86687E79-E582-451D-8F27-8BFE4622DA9AQ34212267-F0B87C76-3FAF-45B8-9E7F-1869DD61E483Q34467407-A320C4EB-8CFD-4585-BF13-0C9330F242B2Q34568808-9238CDC7-1CB9-4782-A5CB-307CCF58C043Q34586418-1D7FA055-E46D-4C26-861B-1AF1497BEC3FQ34719976-A08DCA63-3CAF-4BA9-8E9F-687287635D90Q34769834-6821E131-D5F7-4503-A86B-63FAF22C8088Q34914312-61AF98AC-BD84-45B0-83B1-FE30F4C6D325Q35056738-AB1E8E32-B899-48AD-B2E8-733D51B05AC4Q35070838-2AA7B9C1-6A21-47C6-BAE5-BC9F1452C92CQ35341597-769CE69F-239F-48FB-9D7A-0598688C1670Q35567296-9839EFB5-D4DE-4F48-AF4B-42F7E570DF50Q35596134-6DC3963F-D83D-4886-B87D-00C9FF6BA7D2Q35596169-A00D320E-F145-4C1B-9A6F-029C343F5E4EQ35620664-E798E680-64A0-4C2F-85EB-03CA77AC6BD8Q35868560-E305424B-E6CF-432E-BEA6-E3B3834ABD94Q35969947-E466FC9C-F4F8-4A6C-A4B9-721245F502C9Q36021258-836B577F-BC23-42D7-80FE-DB4170871E63Q36120816-69D3CBF9-FB55-4D7B-904F-81FAF8F0C1E2Q36271954-8E1AE8BC-3513-4F4B-A932-79C275096BBCQ36418108-6F7271CF-0222-4BB2-9D41-DD89EBE136D4Q36525551-47E82BDF-7774-4EBF-AD3F-55C16275682FQ36544962-5832E6F8-DB2B-48D7-9E84-CBE2ED4681F0Q36558683-6E6B82EE-A531-4D83-815E-15173AA45EFFQ36697929-ED8DBEF6-0B53-4A27-840A-86EA2E921FA9Q36852514-3B7E01FF-7FEC-40DA-B13D-5D49A02AF63FQ36910081-02239E56-110E-462D-A42E-DDE1BD2AB1C8Q36953090-C8DEEE2B-3FFC-44D8-9F71-88AD81DC9AE6Q37076348-6EABE99B-F629-4742-9335-1D133AAC54C9Q37079343-C69AD6B2-8B64-4E07-ADBD-CD7559C98F15
P2860
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@ast
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@en
type
label
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@ast
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@en
prefLabel
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@ast
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@en
P2093
P2860
P356
P1476
Multidrug resistance protein 1 ...... d-cerebrospinal fluid barrier.
@en
P2093
A H Schinkel
D D Breimer
D J van den Berg
E C deLange
G L Scheffer
J Wijnholds
M van der Valk
R J Scheper
P2860
P304
P356
10.1172/JCI8267
P407
P577
2000-02-01T00:00:00Z