Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase--a potential target for cancer chemotherapy.

Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase--a potential target for cancer chemotherapy.

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http://www.wikidata.org/entity/Q33890179
Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibitionPhylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memoryRole of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutantImportance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavageMolecular signatures for the Crenarchaeota and the Thaumarchaeota.MetR-regulated Vibrio cholerae metabolism is required for virulence.Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization.Role of pro-297 in the catalytic mechanism of sheep liver serine hydroxymethyltransferase.His230 of serine hydroxymethyltransferase facilitates the proton abstraction step in catalysis.A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling.Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.Characterization of an inducible phenylserine aldolase from Pseudomonas putida 24-1.Interaction of human Dopa decarboxylase with L-Dopa: spectroscopic and kinetic studies as a function of pH.Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis.
P2860

Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase--a potential target for cancer chemotherapy.

Item
http://www.wikidata.org/entity/Q33890179
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Molecular organization, cataly ...... arget for cancer chemotherapy.
@ast
Molecular organization, cataly ...... arget for cancer chemotherapy.
@en
type
label
Molecular organization, cataly ...... arget for cancer chemotherapy.
@ast
Molecular organization, cataly ...... arget for cancer chemotherapy.
@en
prefLabel
Molecular organization, cataly ...... arget for cancer chemotherapy.
@ast
Molecular organization, cataly ...... arget for cancer chemotherapy.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Molecular organization, cataly ...... arget for cancer chemotherapy.
@en
P2093
P304
P31
P356
10.1016/S1357-2725(99)00126-0
P433
P478
P577
P698
P921