Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage.
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HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoterThe Bcl-2 apoptotic switch in cancer development and therapyGene therapy for carcinoma of the breast: Pro-apoptotic gene therapyα-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutationDeletion of Bid impedes cell proliferation and hepatic carcinogenesisBax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesisAntisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis.Bax-dependent regulation of Bak by voltage-dependent anion channel 2.Raloxifene inhibits tumor growth and lymph node metastasis in a xenograft model of metastatic mammary cancer.The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model.Apoptosis in cancer.WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis.BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA.Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment.Reduced expression of ZDHHC2 is associated with lymph node metastasis and poor prognosis in gastric adenocarcinoma.Genetically engineered mice as experimental tools to dissect the critical events in breast cancerNonredundant role of Bax and Bak in Bid-mediated apoptosis.Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?The Bcl-2 family: roles in cell survival and oncogenesis.BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities.Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice.Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein baxMammary involution and breast cancer risk: transgenic models and clinical studies.Bcl2 family proteins in carcinogenesis and the treatment of cancer.Validation of transgenic models of breast cancer: ductal carcinoma in situ (DCIS) and Brca1-mutation-related breast cancer.Deconstructing p53 transcriptional networks in tumor suppression.Mammary cancer gene therapy targeting lymphangiogenesis: VEGF-C siRNA and soluble VEGF receptor-2, a splicing variant.Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer.Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner.Role of Bax in apoptosis of IL-3-dependent cells.S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis.Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK.Neoplastic transformation and tumorigenesis associated with sam68 protein deficiency in cultured murine fibroblasts.Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model.Electrogene therapy using endostatin, with or without suicide gene therapy, suppresses murine mammary tumor growth and metastasis.Involvement of insulin-like growth factor-insulin receptor signal pathway in the transgenic mouse model of medulloblastoma.Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability.
P2860
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P2860
Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@ast
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@en
type
label
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@ast
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@en
prefLabel
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@ast
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@en
P2093
P2860
P356
P1433
P1476
Haploid loss of bax leads to a ...... se at the preneoplastic stage.
@en
P2093
Knudson MC
Korsmeyer SJ
Shibata MA
Yoshidome K
P2860
P304
P356
10.1093/EMBOJ/18.10.2692
P407
P577
1999-05-01T00:00:00Z