Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
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In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cellsSelf-organized Kidney Rudiments: Prospects for Better in vitro Nephrotoxicity AssaysThe role of drug transporters in the kidney: lessons from tenofovirRenal drug transporters and their significance in drug-drug interactionsTenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicityGene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures.Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport.Mitochondrial toxicity and HIV therapy.Development of CMX001 for the Treatment of Poxvirus Infections.Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity.Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.Adefovir nephrotoxicity in a renal allograft recipientEvaluation of chinese-herbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1.Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure.Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2.Treatment strategies using adefovir dipivoxil for individuals with lamivudine-resistant chronic hepatitis B.Acute renal failure in an AIDS patient on tenofovir: a case report.Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirusBMS-986001, an HIV nucleoside reverse transcriptase inhibitor, does not degrade mitochondrial DNA in long-term primary cultures of cells isolated from human kidney, muscle, and adipose tissue.Brincidofovir Is Not a Substrate for the Human Organic Anion Transporter 1: A Mechanistic Explanation for the Lack of Nephrotoxicity Observed in Clinical StudiesAdefovir dipivoxil-induced Fanconi syndrome and its predictive factors: A study of 28 cases.Current and emerging antivirals for the treatment of cytomegalovirus (CMV) retinitis: an update on recent patents.Cidofovir Activity against Poxvirus Infections.Xenobiotic transporters and kidney injury.Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11).Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.Proximal tubular dysfunction associated with tenofovir in an HVC-HIV co-infected patient undergoing HVC therapy.Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug-Drug InteractionsFanconi syndrome due to prolonged use of low-dose adefovir.Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy.Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil.Advances in predictive in vitro models of drug-induced nephrotoxicity.The anti-human cytomegalovirus drug tricin inhibits cyclin-dependent kinase 9.Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series.Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity
P2860
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P2860
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
@zh-hk
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2000年論文
@zh-tw
2000年论文
@wuu
name
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@ast
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@en
type
label
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@ast
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@en
prefLabel
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@ast
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@en
P2093
P1476
Cytotoxicity of antiviral nucl ...... l organic anion transporter 1.
@en
P2093
P304
P577
2000-03-01T00:00:00Z