Protection of neonatal rat brain from hypoxic-ischemic injury by LY379268, a Group II metabotropic glutamate receptor agonist.

Protection of neonatal rat brain from hypoxic-ischemic injury by LY379268, a Group II metabotropic glutamate receptor agonist.

Item
http://www.wikidata.org/entity/Q33893236
Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia.The preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268.Protective role for type 4 metabotropic glutamate receptors against ischemic brain damageDisruptions in the regulation of extracellular glutamate by neurons and glia in the rat striatum two days after diffuse brain injury.The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease miceDriving cellular plasticity and survival through the signal transduction pathways of metabotropic glutamate receptors.Glutamate-mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR-induced release of Ca++ from intracellular stores and is prevented by estradiol.Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia.Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo.AMPA and metabotropic excitoxicity explain subplate neuron vulnerability.Agmatine suppresses nitric oxide production and attenuates hypoxic-ischemic brain injury in neonatal rats.Stimulating ERK/PI3K/NFκB signaling pathways upon activation of mGluR2/3 restores OGD-induced impairment in glutamate clearance in astrocytes.Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model.Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia.
P2860

Protection of neonatal rat brain from hypoxic-ischemic injury by LY379268, a Group II metabotropic glutamate receptor agonist.

Item
http://www.wikidata.org/entity/Q33893236
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@ast
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@en
type
label
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@ast
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@en
prefLabel
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@ast
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Protection of neonatal rat bra ...... ic glutamate receptor agonist.
@en
P2093
P304
P31
P356
10.1097/00001756-199912160-00037
P433
P478
P577
P698
P921