RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response.
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The 2-5A/RNase L/RNase L inhibitor (RLI) [correction of (RNI)] pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cellsISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic virusesUBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activityAntiviral actions of interferonsInterferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylationDown-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cellsDiverse functions of RNase L and implications in pathologyProtein ISGylation modulates the JAK-STAT signaling pathwayThe IRF family, revisitedUbp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signalingAlpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43UBP43 (USP18) specifically removes ISG15 from conjugated proteins.High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction.A newly discovered function for RNase L in regulating translation terminationUbe1L and protein ISGylation are not essential for alpha/beta interferon signaling.Endoribonucleases--enzymes gaining spotlight in mRNA metabolism.USP18 is crucial for IFN-γ-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity.Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemiaLack of RNase L attenuates macrophage functionsGRIM-1, a novel growth suppressor, inhibits rRNA maturation by suppressing small nucleolar RNAsUbp43 gene expression is required for normal Isg15 expression and fetal development.Dysregulation of protein modification by ISG15 results in brain cell injury.Post-transcriptional control of the interferon system.Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs.Gene activity in primary T cells infected with HIV89.6: intron retention and induction of genomic repeats.Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators.Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements.Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome.African swine fever virus multigene family 360 and 530 genes affect host interferon response.UBE1L causes lung cancer growth suppression by targeting cyclin D1.Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence.RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting.Interferon-stimulated gene 15 and the protein ISGylation system.Viruses and the cellular RNA decay machinery.Can't RIDD off viruses.Global changes in STAT target selection and transcription regulation upon interferon treatmentsMultiple functions of USP18.Role for p53 in gene induction by double-stranded RNA.Regulation of mitochondrial mRNA stability by RNase L is translation-dependent and controls IFNalpha-induced apoptosis.Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cells.
P2860
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P2860
RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
RNase-L-dependent destabilizat ...... on of the interferon response.
@ast
RNase-L-dependent destabilizat ...... on of the interferon response.
@en
type
label
RNase-L-dependent destabilizat ...... on of the interferon response.
@ast
RNase-L-dependent destabilizat ...... on of the interferon response.
@en
prefLabel
RNase-L-dependent destabilizat ...... on of the interferon response.
@ast
RNase-L-dependent destabilizat ...... on of the interferon response.
@en
P2093
P2860
P356
P1476
RNase-L-dependent destabilizat ...... on of the interferon response.
@en
P2093
B A Hassel
D V Kalvakolanu
J A Blackford
P2860
P304
P356
10.1074/JBC.275.12.8880
P407
P577
2000-03-01T00:00:00Z