Amyloid precursor protein is trafficked and secreted via synaptic vesicles - Wikidata - awgldk - TriplyDB

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

http://www.wikidata.org/entity/Q33893776

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Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation.Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport.Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells.Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation Global analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.Synaptotagmins interact with APP and promote Aβ generation.The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner.Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.α-Synuclein increases β-amyloid secretion by promoting β-/γ-secretase processing of APP.Locus Coeruleus, norepinephrine and Aβ peptides in Alzheimer's disease Apolipoprotein E acts at pre-synaptic sites...among others APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses.Dysregulation of Amyloid-β Protein Precursor, β-Secretase, Presenilin 1 and 2 Genes in the Rat Selectively Vulnerable CA1 Subfield of Hippocampus Following Transient Global Brain Ischemia.Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies.UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport.Functions of the APP gene family in the nervous system: insights from mouse models.Proteomic analysis of the presynaptic active zone.Deciphering the mechanism underlying late-onset Alzheimer disease.Neuronal activity and amyloid plaque pathology: an update.Amyloid precursor protein processing and bioenergetics.APP-A Novel Player within the Presynaptic Active Zone Proteome.Not just amyloid: physiological functions of the amyloid precursor protein family.Amyloid precursor proteins are constituents of the presynaptic active zone.Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.Synapses in neurodegenerative diseases.Pre-synaptic localization of the γ-secretase-inhibiting protein p24α2 in the mammalian brain.Single-vesicle imaging reveals different transport mechanisms between glutamatergic and GABAergic vesicles.Discrepancy in Expression of β-Secretase and Amyloid-β Protein Precursor in Alzheimer-Related Genes in the Rat Medial Temporal Lobe Cortex Following Transient Global Brain Ischemia.The Association of Amyloid-β Protein Precursor With α- and β-Secretases in Mouse Cerebral Cortex Synapses Is Altered in Early Alzheimer's Disease.Surface Trafficking of APP and BACE in Live Cells.

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Amyloid precursor protein is trafficked and secreted via synaptic vesicles

http://www.wikidata.org/entity/Q33893776

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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type

label

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

@ast

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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prefLabel

Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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Amyloid precursor protein is trafficked and secreted via synaptic vesicles

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Benjamin G Wilhelm

http://www.w3.org/2001/XMLSchema#string

Cora S Thiel

http://www.w3.org/2001/XMLSchema#string

Dietmar Riedel

http://www.w3.org/2001/XMLSchema#string

Jana Hüve

http://www.w3.org/2001/XMLSchema#string

Jürgen Klingauf

http://www.w3.org/2001/XMLSchema#string

Yunfeng Hua

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P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

The synaptic vesicle cycle

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles.

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

Vesicular proteins exocytosed and subsequently retrieved by compensatory endocytosis are nonidentical

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scholarly article

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4

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6

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Teja W. Groemer

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51111304

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21556148

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3083403

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