Blocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetase
about
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valineDiscovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein TranslationtRNA synthetase: tRNA aminoacylation and beyondA paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase.Transfer RNA determinants for translational editing by Escherichia coli valyl-tRNA synthetasePartitioning of tRNA-dependent editing between pre- and post-transfer pathways in class I aminoacyl-tRNA synthetases.Coordination of tRNA synthetase active sites for chemical fidelityFunctional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguityInterstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase.CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase.Exit strategies for charged tRNA from GluRSIn vitro assays for the determination of aminoacyl-tRNA synthetase editing activity.Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activityInhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis.DNA polymerases and aminoacyl-tRNA synthetases: shared mechanisms for ensuring the fidelity of gene expressionQuality Control by Isoleucyl-tRNA Synthetase of Bacillus subtilis Is Required for Efficient Sporulation.The tRNA A76 Hydroxyl Groups Control Partitioning of the tRNA-dependent Pre- and Post-transfer Editing Pathways in Class I tRNA Synthetase.Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing.Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea.Determinants for tRNA-dependent pretransfer editing in the synthetic site of isoleucyl-tRNA synthetase.Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination.Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases.Leucyl-tRNA synthetase from the hyperthermophilic bacterium Aquifex aeolicus recognizes minihelices.tRNA-dependent aminoacyl-adenylate hydrolysis by a nonediting class I aminoacyl-tRNA synthetase.Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain.
P2860
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P2860
Blocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetase
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
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2002年论文
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name
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@ast
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@en
type
label
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@ast
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@en
prefLabel
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@ast
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@en
P2093
P2860
P356
P1476
Blocking site-to-site transloc ...... n of a class I tRNA synthetase
@en
P2093
Anthony C Bishop
Paul Schimmel
Tyzoon K Nomanbhoy
P2860
P304
P356
10.1073/PNAS.012611299
P407
P577
2002-01-08T00:00:00Z