about
Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancyHaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins.On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry.The chimeric ubiquitin ligase SH2-U-box inhibits the growth of imatinib-sensitive and resistant CML by targeting the native and T315I-mutant BCR-ABLPROTAC-induced proteolytic targeting.Nanopediatrics: enabling personalized medicine for children.Emerging Methods in Chemoproteomics with Relevance to Drug Discovery.Targeting oncoproteins for degradation by small molecules in myeloid leukemia.Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.Derailing the UPS of Protein Turnover in Cancer and other Human Diseases
P2860
Q34104101-D1F0038A-C98B-49AD-A33E-949C5CB50B74Q34480529-6AB20874-E74F-4D5C-AF7A-C668DFD9AB19Q36723089-0901A4C0-4127-4A46-98C4-FC0B3BD16782Q37027483-DC453D36-A7CB-4F1A-865A-072335986DD8Q37367304-FD5A90BE-9273-47B4-9AE2-02D3BF25BAF6Q37684727-737E910F-32BE-4439-92C8-BC9BEA764368Q38997223-040256D8-07D5-4EB0-BCD3-73987F6E89E9Q47337952-D7536875-504B-4D54-A9D3-152B10416E43Q49960388-3114BDCC-076E-4C8A-9FA4-AE947E2F63C8Q58919335-1C40E4EE-48F7-41E4-9BEC-1C14A5BFFF3D
P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Protacs for treatment of cancer.
@ast
Protacs for treatment of cancer.
@en
type
label
Protacs for treatment of cancer.
@ast
Protacs for treatment of cancer.
@en
prefLabel
Protacs for treatment of cancer.
@ast
Protacs for treatment of cancer.
@en
P2860
P1433
P1476
Protacs for treatment of cancer.
@en
P2093
Kathleen M Sakamoto
P2860
P2888
P304
P356
10.1203/PDR.0B013E3181D35017
P407
P577
2010-05-01T00:00:00Z
P6179
1007708257