Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase
about
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebMEnzymatic methods for glyco(diversification/randomization) of drugs and small moleculesTargeted metagenomics: finding rare tryptophan dimer natural products in the environmentNatural-product sugar biosynthesis and enzymatic glycodiversification.Natural products version 2.0: connecting genes to molecules.Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesisEngineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties.RebG- and RebM-catalyzed indolocarbazole diversification.Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening.Indolocarbazole natural products: occurrence, biosynthesis, and biological activity.Divergent pathways in the biosynthesis of bisindole natural products.Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine.Total (bio)synthesis: strategies of nature and of chemists.Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environmentCharacterization of an environmental DNA-derived gene cluster that encodes the bisindolylmaleimide methylarcyriarubinCytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691Crystallography gets the jump on the enzymologistsTracking down biotransformation to the genetic level: identification of a highly flexible glycosyltransferase from Saccharothrix espanaensis.Antitumor compounds from marine actinomycetes.Biosynthesis of indolocarbazole and goadsporin, two different heterocyclic antibiotics produced by actinomycetes.Molecular insights on the biosynthesis of antitumour compounds by actinomycetes.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives.Biosynthesis of nitrogen-containing natural products, C7N aminocyclitols and bis-indoles, from actinomycetes.Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032.Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis.Biosynthetic 4,6-dehydratase gene deletion: isolation of a glucosylated jadomycin natural product provides insight into the substrate specificity of glycosyltransferase JadS.OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities.Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis.
P2860
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P2860
Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Deciphering the late steps in ...... f the StaG glycosyltransferase
@ast
Deciphering the late steps in ...... f the StaG glycosyltransferase
@en
type
label
Deciphering the late steps in ...... f the StaG glycosyltransferase
@ast
Deciphering the late steps in ...... f the StaG glycosyltransferase
@en
prefLabel
Deciphering the late steps in ...... f the StaG glycosyltransferase
@ast
Deciphering the late steps in ...... f the StaG glycosyltransferase
@en
P2093
P2860
P50
P1476
Deciphering the late steps in ...... f the StaG glycosyltransferase
@en
P2093
Aaroa P Salas
José A Salas
Jürgen Rohr
P2860
P356
10.1111/J.1365-2958.2005.04777.X
P407
P577
2005-10-01T00:00:00Z