The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice
about
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol dietsSterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolismPurification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol effluxDietary alpha-cyclodextrin lowers low-density lipoprotein cholesterol and alters plasma fatty acid profile in low-density lipoprotein receptor knockout mice on a high-fat dietSPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporterLRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol exportABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytesInhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol effluxNuclear receptors as drug targets for metabolic disease.Prelesional arterial endothelial phenotypes in hypercholesterolemia: universal ABCA1 upregulation contrasts with region-specific gene expression in vivoEnhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo.Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT.The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?Liver-directed gene therapy for dyslipidemia and diabetesLeukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.Deficiency of glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice.Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice.Regulation and mechanisms of macrophage cholesterol effluxABCA1: regulation, trafficking and association with heteromeric proteins.Endothelial expression of human ABCA1 in mice increases plasma HDL cholesterol and reduces diet-induced atherosclerosis.Corticotropin-Releasing Hormone (CRH) Promotes Macrophage Foam Cell Formation via Reduced Expression of ATP Binding Cassette Transporter-1 (ABCA1).Lipidomic Profiling of Liver Tissue from Obesity-Prone and Obesity-Resistant Mice Fed a High Fat DietAssociation of gender, ABCA1 gene polymorphisms and lipid profile in Greek young nurses.Testosterone differentially regulates targets of lipid and glucose metabolism in liver, muscle and adipose tissues of the testicular feminised mouseReverse cholesterol transport and cholesterol efflux in atherosclerosis.Mechanisms of disease: macrophage-derived foam cells emerging as therapeutic targets in atherosclerosis.Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.Lanatoside C Promotes Foam Cell Formation and AtherosclerosisActivation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α.Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo.Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesisBetulin attenuates atherosclerosis in apoE-/- mice by up-regulating ABCA1 and ABCG1.Renal dysfunction potentiates foam cell formation by repressing ABCA1.Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E-deficient mice and cells.Liver X Receptor: Crosstalk Node for the Signaling of Lipid Metabolism, Carbohydrate Metabolism, and Innate Immunity.Micro-RNAs and High-Density Lipoprotein Metabolism.Vascular function during prolonged progression and regression of atherosclerosis in mice.The application of phenotypic high-throughput screening techniques to cardiovascular research.Implications of torcetrapib failure for the future of HDL therapy: is HDL-cholesterol the right target?The protein cargo of HDL: implications for vascular wall biology and therapeutics.
P2860
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P2860
The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@ast
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@en
type
label
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@ast
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@en
prefLabel
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@ast
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@en
P2093
P2860
P921
P356
P1476
The ATP binding cassette trans ...... C57BL/6 and apoE-knockout mice
@en
P2093
Alan T Remaley
Beverly Paigen
Boris L Vaisman
Charles W Joyce
Donald S Fredrickson
Edward D Neufeld
H Bryan Brewer
Jamila Najib-Fruchart
Marcelo J A Amar
Robert F Hoyt
P2860
P304
P356
10.1073/PNAS.012587699
P407
P577
2001-12-18T00:00:00Z