Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer.
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The POU homeodomain protein OCT3 as a potential transcriptional activator for fibroblast growth factor-4 (FGF-4) in human breast cancer cellsAnatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryoPax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens developmentThe transcriptional foundation of pluripotencySox2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cellsCrystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancersYin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implicationThe roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generationFormation of the embryonic organizer is restricted by the competitive influences of Fgf signaling and the SoxB1 transcription factorsRegulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cellsMolecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complexA direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewalMultipotent cell lineages in early mouse development depend on SOX2 functionIdentification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificitySox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiationReciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cellsControl of the embryonic stem cell stateIn vivo time-lapse imaging of cell proliferation and differentiation in the optic tectum of Xenopus laevis tadpoles.Genetic regulation of pituitary gland development in human and mouseCARM1 mediates modulation of Sox2.Coevolution of HMG domains and homeodomains and the generation of transcriptional regulation by Sox/POU complexes.Regulation of retinal homeobox gene transcription by cooperative activity among cis-elements.Preimplantation development regulatory pathway construction through a text-mining approach.Comparison of bone marrow and adipose tissue-derived canine mesenchymal stem cells.SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell stateFunctional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells.Transcription factor heterogeneity and epiblast pluripotency.Sox2 modulates reprogramming of gene expression in two-cell mouse embryos.Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery.Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genesInteractions between pluripotency factors specify cis-regulation in embryonic stem cellsLarge-scale time-lapse microscopy of Oct4 expression in human embryonic stem cell colonies.Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent stateSelective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2.Identification of motifs that are conserved in 12 Drosophila species and regulate midline glia vs. neuron expressionSOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cellsReprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteinsSox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochleaReprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC.
P2860
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P2860
Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Modulation of the activity of ...... last growth factor-4 enhancer.
@ast
Modulation of the activity of ...... last growth factor-4 enhancer.
@en
type
label
Modulation of the activity of ...... last growth factor-4 enhancer.
@ast
Modulation of the activity of ...... last growth factor-4 enhancer.
@en
prefLabel
Modulation of the activity of ...... last growth factor-4 enhancer.
@ast
Modulation of the activity of ...... last growth factor-4 enhancer.
@en
P2093
P2860
P356
P1476
Modulation of the activity of ...... last growth factor-4 enhancer.
@en
P2093
Ambrosetti DC
Basilico C
Schöler HR
P2860
P304
23387-23397
P356
10.1074/JBC.M000932200
P407
P577
2000-07-01T00:00:00Z