Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.

Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.

Item
http://www.wikidata.org/entity/Q33901136
Bromodomains: Translating the words of lysine acetylation into myelin injury and repairProgress in aptamer-mediated drug delivery vehicles for cancer targeting and its implications in addressing chemotherapeutic challenges.The cellular bromodomain protein Brd4 has multiple functions in E2-mediated papillomavirus transcription activationMechanistic analysis of the role of bromodomain-containing protein 4 (BRD4) in BRD4-NUT oncoprotein-induced transcriptional activation.The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification PatternsHisto-genomic stratification reveals the frequent amplification/overexpression of CCNE1 and BRD4 genes in non-BRCAness high grade ovarian carcinoma.A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma.Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma.Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease.miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein.
P2860

Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.

Item
http://www.wikidata.org/entity/Q33901136
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@ast
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@en
type
label
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@ast
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@en
prefLabel
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@ast
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Activation of SOX2 expression ...... tion in NUT midline carcinoma.
@en
P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-13-2658
P407
P433
P478
P50
P577
P698
P932